Affinity DataKd: 0.710nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Affinity DataKd: 0.710nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.10nMpH: 7.0Assay Description:Binding affinity to human recombinant CA2 at 37 degC and pH 7.0 by thermal shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of full length carbonic anhydrase-2 in human erythrocytesMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:In vitro binding to human erythrocyte carbonic anhydrase was determined by fluorescence competition assay employing the fluorescent CA inhibitor dans...More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Mean inhibitory constant towards human carbonic anhydrase II determined by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 8nM ΔG°: -45.7kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 8nM ΔG°: -46.2kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human carbonic anhydrase-2 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to ...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydr...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human CA2 cytosolic isoform after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human CA2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human carbonic anhydrase II.More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory constant against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition constant against human recombinant carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition constant against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition constant against human (cloned) isozyme (hCA II) by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human cloned Carbonic anhydrase II by the CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human Carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cloned CA2 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cloned carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cloned CA2 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase II by spectrophotometry at pH 7.5More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant CA2 cytosolic isoform by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 2 after 15 mins by CO2 hydrase assay at pH 7.5More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 8nMpH: 7.5Assay Description:Inhibition of human recombinant carbonic anhydrase 2 at pH 7.5 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cloned carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase II (CA2)More data for this Ligand-Target Pair

3D Structure (crystal)