Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 6BXY
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455873(CHEMBL4216801)
Affinity DataIC50: 3.60nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455873(CHEMBL4216801)
Affinity DataKd:  9nMAssay Description:Binding affinity to human C-terminal Avi-tagged menin expressed in Escherichia coli BL21 (DE3) cells by bio-layer interferometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50455873(CHEMBL4216801)
Affinity DataKd:  10nMAssay Description:Binding affinity to human Menin expressed in Escherichia coli Rosetta2 (DE3) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)