Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 6CIZ
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM314738(US9611270, Example 38)
Affinity DataIC50: 16nMAssay Description:Inhibition of C-terminal His-tagged recombinant human CYP17A1delta19H mutant expressed in Escherichia coli DH5alpha assessed as decrease in progester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM314738(US9611270, Example 38)
Affinity DataIC50: 174nMAssay Description:Complementary assays were utilized for the quantitative comparison of compound activity data for CYP17A1 and CYP21A2. Progesterone is a substrate for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)