Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 6HKY
TargetKinesin-like protein KIF11(Human)
University of Kwazulu-Natal (Ukzn)

Curated by ChEMBL
LigandPNGBDBM50431893(ARRY-520 | CHEMBL2347655)
Affinity DataIC50: 6nMAssay Description:Inhibition EG5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
University of Kwazulu-Natal (Ukzn)

Curated by ChEMBL
LigandPNGBDBM50431893(ARRY-520 | CHEMBL2347655)
Affinity DataIC50: 6nMAssay Description:Inhibition of Eg5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
University of Kwazulu-Natal (Ukzn)

Curated by ChEMBL
LigandPNGBDBM50431893(ARRY-520 | CHEMBL2347655)
Affinity DataIC50: 6nMAssay Description:Inhibition of microtubule-stimulated Eg5 ATPase activity in human HL-60 cells after 48 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKinesin-like protein KIF11(Human)
University of Kwazulu-Natal (Ukzn)

Curated by ChEMBL
LigandPNGBDBM50431893(ARRY-520 | CHEMBL2347655)
Affinity DataIC50: 18nMAssay Description:Inhibition of His-tagged KSP motor domain (1 to 369) (unknown origin) assessed as inhibition of microtubule-stimulated KSP ATPase activity preincuabt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)