Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) for PDB: 7CMV
TargetD(3) dopamine receptor(Human)
University Centre For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010586(CHEMBL70565 | (-)-1-Propyl-2,3,10,10a-tetrahydro-1...)
Affinity DataKi:  1.40nMAssay Description:Tested for antagonist binding affinity by measuring displacement of [3H]spiperone from Human Dopamine receptor D3 expressed in CHO K-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
University Centre For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010586(CHEMBL70565 | (-)-1-Propyl-2,3,10,10a-tetrahydro-1...)
Affinity DataKi:  1.40nMAssay Description:Tested for antagonist binding affinity by measuring displacement of [3H]spiperone from Human Dopamine receptor D3 expressed in CHO K-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
University Centre For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010586(CHEMBL70565 | (-)-1-Propyl-2,3,10,10a-tetrahydro-1...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-(R)-(+)-7-OH-DPAT from recombinant human D3 receptor expressed in HEK293 cell membranes measured after 90 mins by microbeta scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
University Centre For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010586(CHEMBL70565 | (-)-1-Propyl-2,3,10,10a-tetrahydro-1...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-(R)-(+)-7-OH-DPAT from human D3 receptor expressed in HEK293 cells after 90 mins by microbeta counting based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50010586(CHEMBL70565 | (-)-1-Propyl-2,3,10,10a-tetrahydro-1...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]spiperone from human D3 receptor transfected in HEK293 cell membrane measured after 50 mins by competitive radioligand binding an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
University Centre For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010586(CHEMBL70565 | (-)-1-Propyl-2,3,10,10a-tetrahydro-1...)
Affinity DataKi:  2.14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
University Centre For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010586(CHEMBL70565 | (-)-1-Propyl-2,3,10,10a-tetrahydro-1...)
Affinity DataKi:  3.55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
University Centre For Pharmacy

Curated by ChEMBL
LigandPNGBDBM50010586(CHEMBL70565 | (-)-1-Propyl-2,3,10,10a-tetrahydro-1...)
Affinity DataKi:  7.59nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)