Report error Found 5 Enz. Inhib. hit(s) for PDB: 7DDI
TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
University of Manitoba
Curated by ChEMBL
University of Manitoba
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of [3H]ouabain binding to Digitalis receptor in dog heart microsomesMore data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-3(Human)
Yeda Research and Development
US Patent
Yeda Research and Development
US Patent
Affinity DataKi: 28.8nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-1(Human)
Yeda Research and Development
US Patent
Yeda Research and Development
US Patent
Affinity DataKi: 29.5nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-2/beta-2(Human)
Yeda Research and Development
US Patent
Yeda Research and Development
US Patent
Affinity DataKi: 40.7nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair
TargetSodium/potassium-transporting ATPase subunit alpha-1/beta-1(Human)
Yeda Research and Development
US Patent
Yeda Research and Development
US Patent
Affinity DataKi: 89nMAssay Description:To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo...More data for this Ligand-Target Pair

3D Structure (crystal)