Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 7K0Q
TargetSerine palmitoyltransferase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50461646(CHEBI:582124 | Myriocin)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of human SPT2 transfected in Freestyle293 cells using L-serine and palmitoyl-CoA as substrate preincubated for 60 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine palmitoyltransferase 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50461646(CHEBI:582124 | Myriocin)
Affinity DataEC50:  50nMAssay Description:Inhibition of SPT1 in human MCF7 cells assessed as suppression of 14C-serine incorporation into ceramide incubated for 2 hrs in presence of 4-HPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)