Report error Found 9 Enz. Inhib. hit(s) for PDB: 8IUK
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGF2-alpha from human FP-receptor expressed in CHO-KI cellsMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 3nMAssay Description:In vitro binding at FP human prostaglandin receptor using [3H]PGF-2 alpha as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Affinity for human Prostanoid FP receptor expressed in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at FP receptor in mouse 3T3 fibroblast cells assessed as intracellular calcium mobilization by FLIPRMore data for this Ligand-Target Pair
Affinity DataEC50: 24.5nMAssay Description:Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 24.5nMAssay Description:Agonist activity at FP receptor in Swiss mouse 3T3 cells assessed as [3H]-IP accumulation by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in ovine luteal cells (OLC)More data for this Ligand-Target Pair
Affinity DataEC50: 79nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=75%)More data for this Ligand-Target Pair
Affinity DataKi: 119nMAssay Description:Inhibitory Binding constant (n=2) to Prostanoid FP receptor expressed in bovine corpus luteumMore data for this Ligand-Target Pair