Compile Data Set for Download or QSAR
maximum 50k data
Found 177 for UniProtKB: A4D2K4
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50463479(CHEMBL4249925)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CamK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50463483(CHEMBL4245242)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CamK2B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50463484(CHEMBL4248525)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CamK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50463479(CHEMBL4249925)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of CamK2B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM15211(CHEMBL104264 | H-89 | H89 | HT-89 (H-89) | N-(2-{[...)
Affinity DataKi:  2.97E+4nM ΔG°:  -26.3kJ/moleT: 2°CAssay Description:Protein kinase C, cAMP dependent protein kinase, cGMP dependent protein kinase and myosin light chain kinase activity were measure under conditions d...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM92607(H-88)
Affinity DataKi:  7.13E+4nM ΔG°:  -24.1kJ/moleT: 2°CAssay Description:Protein kinase C, cAMP dependent protein kinase, cGMP dependent protein kinase and myosin light chain kinase activity were measure under conditions d...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.0640nMAssay Description:Inhibition of human CAMK2B using KKALRRQETVDAL as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of CAMK2b (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.0950nMAssay Description:Inhibition of human CAMK2B using KKALRRQETVDAL as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of CAMK2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Cyclin D1-cyclin-dependent kinase 4 by measuring the phosphorylation of RbINGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase type IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM2672(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)
Affinity DataIC50:  25nMAssay Description:Inhibition of Cyclin E-cyclin-dependent kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50217536(CHEMBL2369378)
Affinity DataIC50:  32nMAssay Description:Inhibitory activity of compound against CaMKIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50217537(CHEMBL385035)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity of compound against CaMKIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50363167(CHEMBL1945559)
Affinity DataIC50:  83nMAssay Description:Inhibition of CaMK2 using ATP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM2581(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)
Affinity DataIC50:  184nMAssay Description:Inhibitory activity against Cyclin D1-cyclin-dependent kinase 4 by measuring the phosphorylation of RbINGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50132310(20-ethyl-17,23-dioxa-4,14,20,26-tetraazahexacyclo[...)
Affinity DataIC50:  780nMAssay Description:Inhibition of PKC-beta II mediated IL-8 release from HEK293 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50217535(CHEMBL425458 | desLys-AIP)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity of compound against CaMKIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50217534(CHEMBL413614)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity of compound against CaMKIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50128287(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-methyl-piperidi...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50128288(3-(1-Methyl-1H-indol-3-yl)-4-(1-piperidin-4-yl-1H-...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359359(CHEMBL1929238)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of CAMK2betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50563780(CHEMBL4795714)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2beta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric ho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CAMK2 using autocamtide-2 as substrate after 30 mins by PKLight assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50128282(3-(1H-Indol-3-yl)-4-[1-(1-methyl-piperidin-4-yl)-1...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50554257(CHEMBL4742990)
Affinity DataIC50:  3.85E+3nMAssay Description:Inhibition of human CaMK2betaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50128281(18-dimethylaminomethyl-(18S)-17-oxa-4,14,21-triaza...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50128280(3-[1-(1-Ethyl-piperidin-4-yl)-1H-indol-3-yl]-4-(1-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50128286(3-[1-(1-Isopropyl-piperidin-4-yl)-1H-indol-3-yl]-4...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of Protein kinase C beta 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50133057(17,20,23-trioxa-4,14,26-triazahexacyclo[24.6.1.17,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50554258(CHEMBL4744858)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CaMK2betaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558812(CHEMBL4755698)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CAMK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50355393(BGJ398 | CHEMBL1834657 | US9434697, BGJ398 | US973...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant CAMK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CaMK2beta (1 to 315 residues) using calmodulin a substrate incubated for 40 mins in presence of [gamma-33ATP] by radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50499634(CHEMBL3741589)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CaMK2beta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM106870(US8592455, 70)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CAMK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50133064(17,20,23-trioxa-4,12,14,26,28-pentaazahexacyclo[24...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50135286(CHEMBL3745885)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CAMK2beta using [KKALRRQETVDAL] as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50133058(17,20,23,26-tetraoxa-4,12,14,29,31-pentaazahexacyc...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50133059(17,20,23-trioxa-4,12,14,26-tetraazahexacyclo[24.6....)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Calcium/calmodulin-dependent protein kinase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50128290(3-[1-(1-Cyclopropylmethyl-piperidin-4-yl)-1H-indol...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50388936(CHEMBL2063416)
Affinity DataIC50:  2.59E+4nMAssay Description:Inhibition of CAMK2 using autocamtide-2 as substrate after 30 mins by PKLight assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50128284(3-(1-(1-benzylpiperidin-4-yl)-1H-indol-3-yl)-4-(1-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of CAMK2betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50189603(CHEMBL377734 | N-cyclopropyl-2,4-difluoro-5-((2-(p...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CaMK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50128283(3-[1-(1-Benzyl-pyrrolidin-3-yl)-1H-indol-3-yl]-4-(...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of purified mammalian brain [Ca(2+)]/Calmodulin dependent kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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