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Report error Found 67 for UniProtKB: B2RTT1
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557699BDBM557699(US11466027, Compound 1l | US11358971, Compound 1h)
Affinity DataKi:  63nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557694BDBM557694(US11466027, Compound 1e | US11358971, Compound 1c)
Affinity DataKi:  96nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557693BDBM557693(US11466027, Compound 1d | US11358971, Compound 1b)
Affinity DataKi:  140nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597430BDBM50597430(Dalzanemdor | DALZANEMDOR)
Affinity DataEC50:  150nMAssay Description:Positive allosteric modulation of recombinant human GluN1/GluN2C receptor stably expressed in HEK293 cells assessed as increase in glycine/L-glutamat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557667BDBM557667(US11466027, Compound 1c | US11358971, Compound 1a)
Affinity DataKi:  170nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557701BDBM557701(US11466027, Compound 1n | US11358971, Compound 1j)
Affinity DataKi:  180nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 576021BDBM576021(US11466027, Compound 1f | (R)-2-amino-3-[(7- isopr...)
Affinity DataKi:  220nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557698BDBM557698(US11466027, Compound 1k | US11358971, Compound 1g)
Affinity DataKi:  220nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557702BDBM557702(US11466027, Compound 1o | US11358971, Compound 1k)
Affinity DataKi:  260nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 576017BDBM576017(US11466027, Compound 1b | (R)-2-amino-3-[(7- ethyl...)
Affinity DataKi:  270nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557697BDBM557697(US11466027, Compound 1i | US11358971, Compound 1f)
Affinity DataKi:  360nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498430BDBM50498430(CHEMBL3594112)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant GluN1/GluN2C receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of glutamate-evoked current by whol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557703BDBM557703(US11466027, Compound 1p | US11358971, Compound 1l)
Affinity DataKi:  490nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557696BDBM557696(US11466027, Compound 1h | US11358971, Compound 1e)
Affinity DataKi:  690nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557695BDBM557695(US11466027, Compound 1g | US11358971, Compound 1d)
Affinity DataKi:  860nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 576026BDBM576026(US11466027, Compound 1j | (R)-2-amino-3-[(7- ethox...)
Affinity DataKi:  870nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50611444BDBM50611444(CHEMBL5273123)
Affinity DataEC50:  1.90E+3nMAssay Description:Positive allosteric modulator activity at GluN2C NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a in the presence of L-glut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503149BDBM50503149(CHEMBL4464605)
Affinity DataIC50: 2.00E+3nMAssay Description:Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503153BDBM50503153(CHEMBL4544421)
Affinity DataIC50: 2.60E+3nMAssay Description:Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50436060BDBM50436060(CHEMBL2397100 | US10273214, Example 1390)
Affinity DataEC50:  2.70E+3nMAssay Description:Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 557700BDBM557700(US11466027, Compound 1m | US11358971, Compound 1i)
Affinity DataKi:  3.90E+3nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205849BDBM50205849(CHEMBL3938522 | US10280165, Example 1)
Affinity DataEC50:  4.70E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2C receptor (unknown origin) assessed as increase in glutamate-induced calcium flux measured at time inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503146BDBM50503146(CHEMBL4447266)
Affinity DataIC50: 5.40E+3nMAssay Description:Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503147BDBM50503147(CHEMBL4435232)
Affinity DataEC50:  6.60E+3nMAssay Description:Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440056BDBM50440056(CHEMBL2333944)
Affinity DataIC50: 7.00E+3nMAssay Description:Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324401BDBM50324401((E)-4-(6-Methoxy-2-(3-nitrostyryl)-4-oxoquinazolin...)
Affinity DataIC50: 7.10E+3nMAssay Description:Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C/3B(Human)
H. Lundbeck

US Patent
LigandChemical structure of BindingDB Monomer ID 575980BDBM575980(US11466027, Compound 1a | (R)-2-amino-3-[[7- thien...)
Affinity DataKi:  7.40E+3nMAssay Description:To determine the affinity of the compounds of the present invention a SPA is used. The assay is run in a 384-plate format (OptiPlate-384) where each ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2C(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50164398BDBM50164398(CHEMBL3799213)
Affinity DataEC50:  7.40E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2C NMDAR (unknown origin) expressed in Dox-inducible cells by BD calcium indicator dye based-fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 276103BDBM276103(2-[[1-[4-Chloro-3-(difluoromethoxy)phenyl]triazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GluN2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 276559BDBM276559(US10071988, Example 499 | 2-[[1-[3-(Difluoromethox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GluN2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 436689BDBM436689(US10617676, Example 20 | N-Cyclopropyl-2-[2-oxo-6-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of recombinant human GluN1a/GluN2C expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616996BDBM50616996(CHEMBL5416465)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GluN2C receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50236939BDBM50236939(CHEMBL2333945)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of human GluN2C receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 409486BDBM409486(N-Cyclopropyl-2-[6-[3-(trifluoromethyl)phenyl]pyrr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of recombinant human GluN1a/GluN2C expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498439BDBM50498439(CHEMBL1179566)
Affinity DataIC50: 1.20E+4nMAssay Description:Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007007BDBM50007007(CHEMBL3237281)
Affinity DataEC50:  1.30E+4nMAssay Description:Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379184BDBM50379184(CHEMBL2010868)
Affinity DataIC50: 1.50E+4nMAssay Description:Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50083351BDBM50083351(4-(2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl)phen...)
Affinity DataIC50: 2.91E+4nMAssay Description:Negative allosteric modulation of human GluN2C receptor expressed in xenopus laevis oocytes assessed as reduction in 3 uM glycine-induced channel cur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599751BDBM50599751(CHEMBL5092058)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulator activity at GluN1a/GluN2C (unknown origin) expressed in CHO cells in presence of glutamate by Ca2+ influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503152BDBM50503152(CHEMBL4452216)
Affinity DataEC50:  3.70E+4nMAssay Description:Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503145BDBM50503145(CHEMBL4456824)
Affinity DataIC50: 5.00E+4nMAssay Description:Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086374BDBM50086374(2-[3-(4-Benzyl-piperidin-1-yl)-propylsulfanyl]-1H-...)
Affinity DataIC50: 5.10E+4nMAssay Description:Antagonistic activity against NR1A/2C receptor in frog oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Human)
Sage Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259886BDBM50259886(CHEMBL2333943)
Affinity DataIC50: 6.80E+4nMAssay Description:Negative allosteric modulation of GluN1a/GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glutamate/glyc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259886BDBM50259886(CHEMBL2333943)
Affinity DataIC50: 6.80E+4nMAssay Description:Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503144BDBM50503144(CHEBI:35420 | CHEMBL1179605)
Affinity DataEC50:  8.30E+4nMAssay Description:Positive allosteric modulation of EGFP-fused human GluN2C receptor expressed in HEK293T cells assessed as increase in glycine-induced channel current...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086381BDBM50086381(4-Benzyl-1-[3-(5-methyl-2H-[1,2,4]triazol-3-ylsulf...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against NR1A/2C receptor in frog oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086373BDBM50086373(4-Benzyl-1-[2-(5-methyl-[1,3,4]thiadiazol-2-ylsulf...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against NR1A/2C receptor in frog oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086383BDBM50086383(4-[2-(4-Benzyl-piperidin-1-yl)-ethylsulfanyl]-phen...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against NR1A/2C receptor in frog oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086377BDBM50086377(4-Benzyl-1-[2-(1H-imidazol-2-ylsulfanyl)-ethyl]-pi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against NR1A/2C receptor in frog oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50086388BDBM50086388(4-Benzyl-1-[3-(1H-imidazol-2-ylsulfanyl)-propyl]-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against NR1A/2C receptor in frog oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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