Compile Data Set for Download or QSAR
Report error Found 29 of affinity data for UniProtKB/TrEMBL: P30561
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23927BDBM23927(Tetrachlorodibenzodioxin | 2,3,7,8-Tetrachlorodibe...)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602335BDBM50602335(CHEMBL5186309)
Affinity DataEC50:  0.0580nMAssay Description:Activation of AhR in mouse NIH3T3 cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual-lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92704BDBM92704(Photoaffinity ligand, 1)
Affinity DataKd:  0.440nMpH: 7.5 T: 2°CAssay Description:The equilibrium dissocation constants, KD values for the photoaffinity ligands were determined by a competitive binding assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92706BDBM92706(Photoaffinity ligand, 3)
Affinity DataKd:  0.490nMpH: 7.5 T: 2°CAssay Description:The equilibrium dissocation constants, KD values for the photoaffinity ligands were determined by a competitive binding assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92707BDBM92707(Photoaffinity ligand, 4)
Affinity DataKd:  0.760nMpH: 7.5 T: 2°CAssay Description:The equilibrium dissocation constants, KD values for the photoaffinity ligands were determined by a competitive binding assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92705BDBM92705(Photoaffinity ligand, 2)
Affinity DataKd:  2.10nMpH: 7.5 T: 2°CAssay Description:The equilibrium dissocation constants, KD values for the photoaffinity ligands were determined by a competitive binding assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506039BDBM50506039(CHEMBL1324296 | US11891386, Compound 002)
Affinity DataKd:  3nMAssay Description:Displacement of [3H]TCDD from mouse AhRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92709BDBM92709(Photoaffinity ligand, 6)
Affinity DataKd:  8.10nMpH: 7.5 T: 2°CAssay Description:The equilibrium dissocation constants, KD values for the photoaffinity ligands were determined by a competitive binding assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506039BDBM50506039(CHEMBL1324296 | US11891386, Compound 002)
Affinity DataEC50:  10nMAssay Description:Agonist activity at AhR in mouse Hepa2Dluc cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506039BDBM50506039(CHEMBL1324296 | US11891386, Compound 002)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92711BDBM92711(Photoaffinity ligand, 8)
Affinity DataKd:  11nMpH: 7.5 T: 2°CAssay Description:The equilibrium dissocation constants, KD values for the photoaffinity ligands were determined by a competitive binding assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92708BDBM92708(Photoaffinity ligand, 5)
Affinity DataKd:  13nMpH: 7.5 T: 2°CAssay Description:The equilibrium dissocation constants, KD values for the photoaffinity ligands were determined by a competitive binding assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439845BDBM50439845(CHEMBL2420083)
Affinity DataIC50: 21nMAssay Description:Displacement of 2-azido-3-[125I]7,8-dibromodibenzo-pdioxin from C57BL/6J mouse liver AhR incubated for 20 mins by gamma counting based autoradiograph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014323BDBM50014323(CHEMBL283196 | alpha-naphthoflavone | 2-PHENYL-4H-...)
Affinity DataIC50: 25nMAssay Description:Displacement of 2-azido-3-[125I]7,8-dibromodibenzo-pdioxin from C57BL/6J mouse liver AhR incubated for 20 mins by gamma counting based autoradiograph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602335BDBM50602335(CHEMBL5186309)
Affinity DataEC50:  71nMAssay Description:Activation of AhR in mouse Hepa1c1c7 cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605060BDBM50605060(CHEMBL5198290 | US11891386, Compound 004)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239186BDBM50239186(CHEBI:50182 | 1,1-Bis(3''-Indolyl)Methane | 3,3''-...)
Affinity DataKd:  90nMAssay Description:Displacement of 2-azido-3-[125I]7,8-dibromodibenzo-pdioxin from C57BL/6J mouse liver AhRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92710BDBM92710(Photoaffinity ligand, 7)
Affinity DataKd:  113nMpH: 7.5 T: 2°CAssay Description:The equilibrium dissocation constants, KD values for the photoaffinity ligands were determined by a competitive binding assay. More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605061BDBM50605061(CHEMBL5179114)
Affinity DataKi:  800nMAssay Description:Displacement of [3H]TCDD from mouse AhR expressed in mouse Hepa1c1c7 cells cytosol incubated for 2 hrs by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015301BDBM50015301(CHEMBL3263111)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at AHR in FVB/N mouse primary mammary epithelial cells assessed as blockade of mammary branching morphogenesis after 144 hrs by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015302BDBM50015302(CHEMBL3263112)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at AHR in FVB/N mouse primary mammary epithelial cells assessed as blockade of mammary branching morphogenesis after 144 hrs by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015303BDBM50015303(CHEMBL3263118)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at AHR in FVB/N mouse primary mammary epithelial cells assessed as blockade of mammary branching morphogenesis after 144 hrs by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015304BDBM50015304(CHEMBL3263119)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at AHR in FVB/N mouse primary mammary epithelial cells assessed as blockade of mammary branching morphogenesis after 144 hrs by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357344BDBM50357344(CHEMBL1916902)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50015305BDBM50015305(CHEMBL3263120)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at AHR in FVB/N mouse primary mammary epithelial cells assessed as blockade of mammary branching morphogenesis after 144 hrs by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357339BDBM50357339(CHEMBL1916897)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357333BDBM50357333(CHEMBL1916891)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357322BDBM50357322(CHEMBL1916880)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239186BDBM50239186(CHEBI:50182 | 1,1-Bis(3''-Indolyl)Methane | 3,3''-...)
Affinity DataEC50:  7.80E+4nMAssay Description:Displacement of 2-azido-3-[125I]7,8-dibromodibenzo-pdioxin from C57BL/6J mouse liver AhR relative to TCDDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed