Compile Data Set for Download or QSAR
Report error Found 28 of affinity data for UniProtKB/TrEMBL: P49651
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50409654BDBM50409654(CHEMBL2021421)
Affinity DataEC50:  1nMAssay Description:Agonists activity was evaluated by release of [Ca2+] release of HEK 293 cells stably transfected with rat-brain P2Y purinoceptor 1 (P2Y1-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50118232BDBM50118232(ATP, 2-meS | CHEMBL336208 | 2-MeSATP)
Affinity DataEC50:  1nMAssay Description:Concentration required for calcium mobilization at rat purinergic 2Y1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50410189BDBM50410189(CHEMBL2093075)
Affinity DataEC50:  1nMAssay Description:Concentration required for calcium mobilization at rat purinergic 2Y1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370180BDBM50370180(CHEMBL607612)
Affinity DataEC50:  2nMAssay Description:Agonists activity was evaluated by release of [Ca2+] release of HEK 293 cells stably transfected with rat-brain P2Y purinoceptor 1 (P2Y1-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422407BDBM50422407(CHEMBL2364735)
Affinity DataEC50:  2nMAssay Description:Agonists activity was evaluated by release of [Ca2+] release of HEK 293 cells stably transfected with rat-brain P2Y purinoceptor 1 (P2Y1-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50267999BDBM50267999(CHEMBL601711 | ({[({[(2R,3S,4R,5R)-5-[6-amino-2-(m...)
Affinity DataEC50:  2.60nMAssay Description:Concentration required for calcium mobilization at rat purinergic 2Y1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50267999BDBM50267999(CHEMBL601711 | ({[({[(2R,3S,4R,5R)-5-[6-amino-2-(m...)
Affinity DataEC50:  2.60nMAssay Description:Concentration required for calcium mobilization at rat purinergic 2Y1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50267999BDBM50267999(CHEMBL601711 | ({[({[(2R,3S,4R,5R)-5-[6-amino-2-(m...)
Affinity DataEC50:  2.60nMAssay Description:Agonists activity was evaluated by release of [Ca2+] release of HEK 293 cells stably transfected with rat-brain P2Y purinoceptor 1 (P2Y1-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398072BDBM50398072(CHEMBL2181943)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at rat P2Y1R expressed in HEK293 cells assessed as release of intracellular calcium by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422406BDBM50422406(2-Chloroadenosine Triphosphate Tetrasodium | CHEMB...)
Affinity DataEC50:  3.60nMAssay Description:Agonists activity was evaluated by release of [Ca2+] release of HEK 293 cells stably transfected with rat-brain P2Y purinoceptor 1 (P2Y1-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370496BDBM50370496(CHEMBL610595)
Affinity DataEC50:  4.5nMAssay Description:Concentration required for calcium mobilization at rat purinergic 2Y1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422408BDBM50422408(CHEMBL2364736)
Affinity DataEC50:  4.5nMAssay Description:Agonists activity was evaluated by release of [Ca2+] release of HEK 293 cells stably transfected with rat-brain P2Y purinoceptor 1 (P2Y1-R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435007BDBM50435007(CHEMBL2386493)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at rat brain P2Y1R transfected in HEK293 cells assessed as induction of intracellular calcium mobilization by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370496BDBM50370496(CHEMBL610595)
Affinity DataEC50:  4.5nMAssay Description:Concentration required for calcium mobilization at rat purinergic 2Y1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50410192BDBM50410192(CHEMBL2093074)
Affinity DataEC50:  9.40nMAssay Description:Concentration required for calcium mobilization at rat purinergic 2Y1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50410191BDBM50410191(CHEMBL2092819)
Affinity DataEC50:  20nMAssay Description:Concentration required for calcium mobilization at rat purinergic 2Y1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176056BDBM50176056(2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE) | 9H-p...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398072BDBM50398072(CHEMBL2181943)
Affinity DataEC50:  28nMAssay Description:Agonist activity at rat P2Y1R assessed as glucose-dependent insulin secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50267999BDBM50267999(CHEMBL601711 | ({[({[(2R,3S,4R,5R)-5-[6-amino-2-(m...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at rat pancreas P2Y1 receptor assessed as enhancement of insulin secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184368BDBM50184368(A(5')p3(5')A | Adenosine(3)triphosphate adenosine ...)
Affinity DataEC50:  60nMAssay Description:Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184370BDBM50184370(pentakis(tributylamine) [(2R,3S,4R,5R)-5-(6-amino-...)
Affinity DataEC50:  63nMAssay Description:Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50410190BDBM50410190(CHEMBL2092818)
Affinity DataEC50:  75nMAssay Description:Concentration required for calcium mobilization at rat purinergic 2Y1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50118242BDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataEC50:  100nMAssay Description:Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366480BDBM50366480(ATP | ADENOSINE TRIPHOSPHATE)
Affinity DataEC50:  200nMAssay Description:Agonist activity at rat P2Y1R expressed in HEK293 cells assessed as release of intracellular calcium by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370497BDBM50370497(CHEMBL611086)
Affinity DataEC50:  200nMAssay Description:Concentration required for calcium mobilization at rat purinergic 2Y1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2BDBM2(CHEMBL14249 | ({[({[(2R,3S,4R,5R)-5-(6-amino-9H-pu...)
Affinity DataEC50:  590nMAssay Description:Concentration required for calcium mobilization at rat purinergic 2Y1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184371BDBM50184371([bis({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4...)
Affinity DataEC50:  900nMAssay Description:Activity against rat P2Y1-GFP transfected in HEK293 cells by intracellular calcium increaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Rat)
Bar-Ilan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370497BDBM50370497(CHEMBL611086)
Affinity DataEC50: >1.00E+3nMAssay Description:Concentration required for calcium mobilization at rat purinergic 2Y1 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed