Compile Data Set for Download or QSAR
Report error Found 204 for UniProtKB: Q61239
LigandChemical structure of BindingDB Monomer ID 50126036BDBM50126036(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataEC50:  0.100nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50135353BDBM50135353(5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataEC50:  0.5nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50126320BDBM50126320(1-{[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-m...)
Affinity DataEC50:  0.5nMAssay Description:Inhibition of Ras farnesylation in Human Ha-Ras oncogene-transformed BALB/c 3T3 cells (EJ3 cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50126322BDBM50126322(4-Cyano-5-naphthalen-1-yl-3,6-dihydro-2H-pyridine-...)
Affinity DataEC50: >1nMAssay Description:Inhibition of Ras farnesylation in Human Ha-Ras oncogene-transformed BALB/c 3T3 cells (EJ3 cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153785BDBM50153785(4-((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)-2-...)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153168BDBM50153168(6-({[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-am...)
Affinity DataEC50:  1.34nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153170BDBM50153170(6-({[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-me...)
Affinity DataEC50:  1.57nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50126335BDBM50126335(R-115777 | 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1...)
Affinity DataEC50:  1.60nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50126335BDBM50126335(R-115777 | 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1...)
Affinity DataEC50:  1.60nMAssay Description:Inhibition of Ras farnesylation in H-Ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153797BDBM50153797(6-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)me...)
Affinity DataEC50:  1.60nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153169BDBM50153169(3-Benzo[1,3]dioxol-5-yl-4-[3-(4-cyano-benzyl)-3H-i...)
Affinity DataEC50:  1.65nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50126041BDBM50126041(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataEC50:  2.74nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50126317BDBM50126317(1-{2-[3-(4-Cyano-benzyl)-3H-imidazol-4-yl]-acetyl}...)
Affinity DataEC50:  3.90nMAssay Description:Inhibition of Ras farnesylation in Human Ha-Ras oncogene-transformed BALB/c 3T3 cells (EJ3 cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 16181BDBM16181(1-[2-(4-cyanophenyl)-2-hydroxy-2-(1-methyl-1H-imid...)
Affinity DataEC50:  4nMAssay Description:Inhibition of Ras farnesylation in Human Ha-Ras oncogene-transformed BALB/c 3T3 cells (EJ3 cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50177232BDBM50177232(4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...)
Affinity DataIC50: 5nMAssay Description:Anchorage-independent growth of transformed NIH3T3 cells in soft agarMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50177232BDBM50177232(4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...)
Affinity DataIC50: 5.20nMAssay Description:Anchorage-independent growth of transformed NIH3T3 cells in soft agarMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 13382BDBM13382(CHEMBL158553 | 3-(3-chlorophenyl)-4-{[(4-cyanophen...)
Affinity DataEC50:  5.20nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153166BDBM50153166(3''-Chloro-6-[3-(4-cyano-benzyl)-3H-imidazol-4-ylm...)
Affinity DataEC50:  7.70nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153166BDBM50153166(3''-Chloro-6-[3-(4-cyano-benzyl)-3H-imidazol-4-ylm...)
Affinity DataEC50:  7.70nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50151520BDBM50151520(3-{4-(3-chlorophenyl)-5-[4-cyanophenyl(1-methyl-1H...)
Affinity DataEC50:  9nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50151519BDBM50151519(4-[[1-(3-Chloro-benzyl)-4-(3-chloro-phenyl)-6-oxo-...)
Affinity DataEC50:  10nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50151521BDBM50151521(4-(3-Chloro-phenyl)-5-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataEC50:  11nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50157246BDBM50157246(6''-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(...)
Affinity DataEC50:  11nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50157270BDBM50157270(6''-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(...)
Affinity DataEC50:  13nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50151515BDBM50151515(4-[[4-(3-Chloro-phenyl)-1-(3-fluoro-benzyl)-6-oxo-...)
Affinity DataEC50:  15nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50151516BDBM50151516(5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataEC50:  15nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 17325BDBM17325(CHEMBL29982 | (2S)-2-[(4-{[butyl(2-cyclohexylethyl...)
Affinity DataEC50:  16nMAssay Description:Effective concentration against H-ras processing in NIH 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153164BDBM50153164(N-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-N-(5...)
Affinity DataEC50:  16nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153783BDBM50153783(5-[5-(2-Benzo[1,3]dioxol-5-yl-4-cyano-benzyloxymet...)
Affinity DataEC50:  16nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153171BDBM50153171(6-{3-[3-(4-Cyano-benzyl)-3H-imidazol-4-yl]-3-hydro...)
Affinity DataEC50:  16.7nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153776BDBM50153776(5-((5-(((5-cyano-3'-ethoxybiphenyl-2-yl)methoxy)me...)
Affinity DataEC50:  17nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50097814BDBM50097814((S)-2-[(5-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of mammalian H-Ras processing in NIH 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153769BDBM50153769(5-(3-Chloro-phenyl)-6-({[3-(4-cyano-benzyl)-3H-imi...)
Affinity DataEC50:  21nMAssay Description:Inhibition of Ras farnesylation in H-Ras transformed NIH3T3 cells at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153173BDBM50153173(6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethy...)
Affinity DataEC50:  21.9nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50126323BDBM50126323(1-{3-[3-(4-Cyano-benzyl)-3H-imidazol-4-yl]-propion...)
Affinity DataEC50:  28nMAssay Description:Inhibition of Ras farnesylation in Human Ha-Ras oncogene-transformed BALB/c 3T3 cells (EJ3 cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153791BDBM50153791(6-((5-((2-(benzo[d][1,3]dioxol-5-yl)-4-cyanobenzyl...)
Affinity DataEC50:  29nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50157277BDBM50157277(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  30nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50126326BDBM50126326(1-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataEC50:  31nMAssay Description:Inhibition of Ras farnesylation in Human Ha-Ras oncogene-transformed BALB/c 3T3 cells (EJ3 cells)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153175BDBM50153175(6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethy...)
Affinity DataEC50:  32nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153796BDBM50153796(6-(((1-(4-chlorobenzyl)-1H-imidazol-5-yl)methoxy)m...)
Affinity DataEC50:  34nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50079787BDBM50079787(methyl 2-[1-[5-amino-2-isopropyl-6-sulfanyl-(2S,3E...)
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153174BDBM50153174(6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethy...)
Affinity DataEC50:  52nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153174BDBM50153174(6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethy...)
Affinity DataEC50:  52nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50157238BDBM50157238(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  53nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153167BDBM50153167(6-{3-[3-(4-Cyano-benzyl)-3H-imidazol-4-yl]-3-hydro...)
Affinity DataEC50:  57.5nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153778BDBM50153778(6-[3-(4-Cyano-3-naphthalen-1-yl-benzyl)-3H-imidazo...)
Affinity DataEC50:  60nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50327974BDBM50327974(N-Benzyl,N-{2-[(4-Cyanophenyl)-(3-methyl-3H-imidaz...)
Affinity DataIC50: 70nMAssay Description:Inhibition of H-Ras farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50153792BDBM50153792(4'-acetyl-6-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)...)
Affinity DataEC50:  77nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50157254BDBM50157254(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataEC50:  85nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50157256BDBM50157256(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  89nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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