Compile Data Set for Download or QSAR
Report error Found 252 of affinity data for UniProtKB/TrEMBL: Q8R431
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160283BDBM50160283(CHEMBL3787346)
Affinity DataIC50: 0.0780nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642986BDBM50642986(CHEMBL6067709)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of rat MAGL expressed in human HeLa cells using 2-arachidonoylglycerol as substrate preincubated with compound for 20 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160284BDBM50160284(CHEMBL3785379)
Affinity DataIC50: 0.159nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50065646BDBM50065646(CHEMBL3087181)
Affinity DataIC50: 0.214nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643000BDBM50643000(CHEMBL5569248)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of rat MAGL expressed in human HeLa cells using 2-arachidonoylglycerol as substrate preincubated with compound for 20 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643000BDBM50643000(CHEMBL5569248)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160284BDBM50160284(CHEMBL3785379)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160284BDBM50160284(CHEMBL3785379)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of rat MAGL expressed in human HeLa cells using 2-arachidonoylglycerol as substrate preincubated with compound for 20 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450752BDBM50450752(CHEMBL4216513)
Affinity DataIC50: 0.269nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102829BDBM50102829(CHEMBL3356956)
Affinity DataIC50: 0.589nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160284BDBM50160284(CHEMBL3785379)
Affinity DataIC50: 0.827nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099618BDBM50099618(CHEMBL1232635)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099618BDBM50099618(CHEMBL1232635)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642985BDBM50642985(CHEMBL5591381)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of rat MAGL expressed in human HeLa cells using 2-arachidonoylglycerol as substrate preincubated with compound for 20 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642991BDBM50642991(CHEMBL5573137)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of rat MAGL expressed in human HeLa cells using 2-arachidonoylglycerol as substrate preincubated with compound for 20 mins followed by sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160284BDBM50160284(CHEMBL3785379)
Affinity DataIC50: 10nMAssay Description:Inhibition of MAGL in rat brain membranes preincubated for 20 mins followed by fluorophosphonate-rhodamine addition measured after 30 mins by competi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2017
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514172BDBM50514172(CHEMBL4536072)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179950BDBM179950(US9133148, 3a)
Affinity DataIC50: 14nMAssay Description:Inhibition of rat MAGL preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514166BDBM50514166(CHEMBL4448448)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514173BDBM50514173(CHEMBL4463191)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359050BDBM50359050(CHEMBL1922513)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant rat N-terminal histidine tagged MAGL expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520895BDBM50520895(CHEMBL4472033)
Affinity DataIC50: 20nMAssay Description:Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514167BDBM50514167(CHEMBL4560077)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60622BDBM60622(BDBM50300355 | US9133148, A | US11753371, Compound...)
Affinity DataIC50: 25nMAssay Description:Inhibition of rat MAGL expressed in monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520905BDBM50520905(CHEMBL4437385)
Affinity DataIC50: 33nMAssay Description:Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435396BDBM50435396(CHEMBL2391916)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50643019BDBM50643019(CHEMBL5571217)
Affinity DataIC50: 35nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520885BDBM50520885(CHEMBL4521157)
Affinity DataIC50: 37nMAssay Description:Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450761BDBM50450761(CHEMBL4202705)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant rat N-terminal histidine tagged MAGL expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 179929BDBM179929(US9133148, 1a)
Affinity DataIC50: 43nMAssay Description:Inhibition of rat MAGL preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514173BDBM50514173(CHEMBL4463191)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant rat MGL C208A mutant expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520890BDBM50520890(CHEMBL4445089)
Affinity DataIC50: 52nMAssay Description:Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514170BDBM50514170(CHEMBL4515209)
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514173BDBM50514173(CHEMBL4463191)
Affinity DataIC50: 54nMAssay Description:Inhibition of recombinant rat MGL C201A mutant expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514182BDBM50514182(CHEMBL3219170)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359050BDBM50359050(CHEMBL1922513)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359050BDBM50359050(CHEMBL1922513)
Affinity DataIC50: 59nMAssay Description:Inhibition of rat recombinant N-terminal his-tagged MAGL expressed in Escherichia coli DH5alpha assessed as 2-oleoylglycerol hydrolysis after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 61908BDBM61908(KUC103657N | cid_351236 | 2-methyl-1,2-benzothiazo...)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50435396BDBM50435396(CHEMBL2391916)
Affinity DataIC50: 73nMAssay Description:Inhibition of recombinant rat MGL C208A mutant expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520896BDBM50520896(CHEMBL4463729)
Affinity DataIC50: 76nMAssay Description:Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514166BDBM50514166(CHEMBL4448448)
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant rat MGL C208A mutant expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 66023BDBM66023(2-octyl-1,2-thiazol-3-one | cid_33528 | 2-octyl-3-...)
Affinity DataIC50: 88nMAssay Description:Inhibition of recombinant rat N-terminal histidine tagged MAGL expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359049BDBM50359049(CHEMBL1922512)
Affinity DataIC50: 88nMAssay Description:Inhibition of rat recombinant N-terminal his-tagged MAGL expressed in Escherichia coli DH5alpha assessed as 2-oleoylglycerol hydrolysis after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450775BDBM50450775(CHEMBL4207055 | med.21724, Compound 142)
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant rat MAGL expressed in Escherichia coli using 2-AG as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81363BDBM81363(Pristimerin)
Affinity DataIC50: 93nMT: 2°CAssay Description:Purified recombinant rat MGL was prepared and enzyme activity was assayed. More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2011
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481947BDBM50481947(CHEBI:8416 | GNF-Pf-476 | Pristimerine | PRISTIMER...)
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant rat MAGL by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514180BDBM50514180(CHEMBL4439900)
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520904BDBM50520904(CHEMBL4541769)
Affinity DataIC50: 98nMAssay Description:Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520894BDBM50520894(CHEMBL4540953)
Affinity DataIC50: 98nMAssay Description:Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520901BDBM50520901(CHEMBL4472005)
Affinity DataIC50: 98nMAssay Description:Inhibition of purified rat MGL using AHMMCE as fluorogenic substrate preincubated for 15 mins followed by substrate addition measured at 15 mins inte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
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