Compile Data Set for Download or QSAR
Report error Found 554 for UniProtKB: Q96F46
TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740381BDBM740381(5-cyano-N-((1S)-1- cyclohexyl-2-((2- (methylcarbam...)
Affinity DataIC50: 5.5nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740369BDBM740369(N-(1-(4- ethylcyclohexyl)-2-((2- (methylcarbamoyl)...)
Affinity DataIC50: 5.60nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740335BDBM740335(N-((1S)-1-cyclohexyl- 2-((2- (methylcarbamoyl)-2- ...)
Affinity DataIC50: 5.80nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548167BDBM548167(WO2022091056, Example 158)
Affinity DataIC50: 6.10nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740198BDBM740198(N-(1-(6-chloro-1,2,3,4- tetrahydronaphthalen-2- yl...)
Affinity DataIC50: 6.30nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740228BDBM740228(N-(1-(5-chloro-1,2,3,4- tetrahydronaphthalen-2- yl...)
Affinity DataIC50: 6.5nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740169BDBM740169(N-((1S)-1-((1r,4S)-4- ethylcyclohexyl)-2-((2- (met...)
Affinity DataIC50: 7nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740323BDBM740323(N-(1-(4- ethylcyclohexyl)-2-((2- ((R)-4-isopropyl-...)
Affinity DataIC50: 7.5nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548005BDBM548005(2,4-dimethyl-3-(4-((S)-2-(1-methyl-1H-pyrazole-5-c...)
Affinity DataIC50: 8nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

LigandChemical structure of BindingDB Monomer ID 727042BDBM727042(N-[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50574352BDBM50574352(CHEMBL4876088 | US12252491, Example 19)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727041BDBM727041(N-[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50574355BDBM50574355(CHEMBL4874078 | US12252491, Example 26)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50574356BDBM50574356(CHEMBL4845695 | US12252491, Example 27)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727048BDBM727048(N-[(S)-(4,4-Difluorocyclohexyl)-[7-[(1S)-2-methoxy...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727049BDBM727049(4-Cyclopropyl-N-[(S)-(4,4-difluorocyclohexyl)-[7-[...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727047BDBM727047(N-[(S)-(4,4-difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50574353BDBM50574353(CHEMBL4860250 | US12252491, Example 20)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50574354BDBM50574354(CHEMBL4866932 | US12252491, Example 21)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50574357BDBM50574357(CHEMBL4855085 | US12252491, Example 28)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727035BDBM727035(N-[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726971BDBM726971(N-[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740325BDBM740325(N-((1S)-1-cyclohexyl- 2-((2- (methylcarbamoyl)-2- ...)
Affinity DataIC50: 9.5nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740131BDBM740131(N-(1-(4- isopropylcyclohexyl)-2- ((2-(methylcarbam...)
Affinity DataIC50: 10nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740397BDBM740397(N-(1-(4- ethylcyclohexyl)-2-((2- (methylcarbamoyl)...)
Affinity DataIC50: 10nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740363BDBM740363(N-((1S)-1-cyclohexyl- 2-((2-(((R)-1- cyclohexyl-2-...)
Affinity DataIC50: 10nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726976BDBM726976(N-[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 10.6nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740184BDBM740184(N-((1S)-1-cyclohexyl-2- ((2-(5-methyl-2-oxo-5- (tr...)
Affinity DataIC50: 10.9nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740215BDBM740215(N-((1S)-1-cycloheptyl- 2-((2-((R)-4-isopropyl- 2-o...)
Affinity DataIC50: 11nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727046BDBM727046(N-[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 11.4nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740328BDBM740328(N-(2-((2-((R)-4- isopropyl-2- oxoimidazolidin-1-yl...)
Affinity DataIC50: 12nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548056BDBM548056(WO2022091056, Example 48)
Affinity DataIC50: 12nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

LigandChemical structure of BindingDB Monomer ID 726969BDBM726969(N-[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 13nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548188BDBM548188(WO2022091056, Example 196 | WO2022091056, Example ...)
Affinity DataIC50: 14nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548093BDBM548093(WO2022091056, Example 84)
Affinity DataIC50: 14nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548071BDBM548071(WO2022091056, Example 62)
Affinity DataIC50: 15nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740339BDBM740339(N-((1S)-1-cyclohexyl- 2-((2- (methylcarbamoyl)-2- ...)
Affinity DataIC50: 15nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740329BDBM740329(N-((1S)-1-cyclohexyl- 2-((2-(5-ethyl-5-methyl- 2- ...)
Affinity DataIC50: 15nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726828BDBM726828(N-[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 15.2nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740204BDBM740204(5-((S)-2-cyclohexyl-2- (1-methyl-1H-pyrazole- 5- c...)
Affinity DataIC50: 15.3nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726975BDBM726975(N-[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 15.5nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726720BDBM726720(3-Cyclopropyl-N-[(S)-(4,4-difluorocyclohexyl)-[7-[...)
Affinity DataIC50: 15.7nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740282BDBM740282(N-((1S)-1-(4,4- difluorocyclohexyl)-2- oxo-2-((2-(...)
Affinity DataIC50: 15.9nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740401BDBM740401(N-((1S)-1-cyclohexyl- 2-((2- (methylcarbamoyl)-2- ...)
Affinity DataIC50: 16nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548061BDBM548061(WO2022091056, Example 53)
Affinity DataIC50: 16nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548020BDBM548020(WO2022091056, Example 13a)
Affinity DataIC50: 16nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740361BDBM740361(N-((1S)-1-cyclohexyl- 2-((2-(((S)-1- cyclohexyl-2-...)
Affinity DataIC50: 16nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 740390BDBM740390(N-((2S)-1,1- dicyclopropyl-3-((2- ((dicyclopropylm...)
Affinity DataIC50: 16.5nMAssay Description:Compounds disclosed herein were tested for blocking of human IL-17A (Cat: C774, novoprotein) protein with its receptor human IL-17RA (Cat: C153, novo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/15/2025
Entry Details
US Patent

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548006BDBM548006(4-chloro-3-(4-((S)-2-cyclohexyl-2-(1-methyl-1H-pyr...)
Affinity DataIC50: 17nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

TargetInterleukin-17 receptor A/(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 548055BDBM548055(WO2022091056, Example 47)
Affinity DataIC50: 17nMAssay Description: Dilutions of test compounds in DMSO are plated onto white low-volume 384-well plates (Greiner, #784075). Specifically, solutions of graded concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
WIPO WO2022091056

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