Compile Data Set for Download or QSAR
Report error Found 1784 for UniProtKB: O00459
LigandPNGBDBM295666(US10112932, Compound 102 | (S)-2-cyclobutyl-2-((2-...)
Affinity DataKi: >1.00E+3nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

LigandPNGBDBM295668(US10112932, Compound 104 | (S)-2-cyclopropyl-2-((2...)
Affinity DataKi:  813nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

LigandPNGBDBM295669(US10112932, Compound 105 | (S)-2-cyclopropyl-2-((2...)
Affinity DataKi:  341nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

LigandPNGBDBM295667(US10112932, Compound 103 | (S)-2-cyclopropyl-2-((2...)
Affinity DataKi:  335nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

LigandPNGBDBM295671(US10112932, Compound 107 | (S)-2-((2-((S)-4-(diflu...)
Affinity DataKi:  132nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

LigandPNGBDBM295670(US10112932, Compound 106 | (S)-2-((2-((S)-4-(fluor...)
Affinity DataKi:  122nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

LigandPNGBDBM295665(US10112932, Compound 101 | (S)-2-((2-((S)-4-(diflu...)
Affinity DataKi:  99.7nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

LigandPNGBDBM25028(4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpipera...)
Affinity DataKi:  70.2nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

LigandPNGBDBM50434806(CHEMBL2387080 | Taselisib | GDC 0032 | 2-(4-(2-(1-...)
Affinity DataKi:  53nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent

LigandPNGBDBM288892(US10092563, Compound 27)
Affinity DataIC50: 5.60E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288950(US10092563, Compound 87)
Affinity DataIC50: 1.00E+7nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288952(US10092563, Compound 89)
Affinity DataIC50: 4.50E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288966(US10092563, Compound 103)
Affinity DataIC50: 2.20E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288967(US10092563, Compound 104)
Affinity DataIC50: 1.00E+7nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288968(US10092563, Compound 105)
Affinity DataIC50: 1.90E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288971(US10092563, Compound 108)
Affinity DataIC50: 6.10E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288973(US10092563, Compound 110)
Affinity DataIC50: 1.40E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288975(US10092563, Compound 112)
Affinity DataIC50: 7.80E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288978(US10092563, Compound 115)
Affinity DataIC50: 1.80E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288983(US10092563, Compound 120)
Affinity DataIC50: 1.20E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288985(US10092563, Compound 122)
Affinity DataIC50: 1.80E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288986(US10092563, Compound 124)
Affinity DataIC50: 1.30E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288994(US10092563, Compound 132)
Affinity DataIC50: 1.00E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288996(US10092563, Compound 134)
Affinity DataIC50: 2.20E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288997(US10092563, Compound 135)
Affinity DataIC50: 4.70E+6nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM362061((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50: 2.60E+6nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandPNGBDBM362063((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50: 6.60E+6nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandPNGBDBM362064(US10221197, Compound 58 | (S)-1-(3-(2-(1-((6-amino...)
Affinity DataIC50: 1.30E+6nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandPNGBDBM362068((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50: 1.13E+6nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandPNGBDBM362100(US10221197, Compound 94 | (S)-1-(3-(2-(1-((4-amino...)
Affinity DataIC50: 5.50E+6nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandPNGBDBM362113((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50: 4.80E+6nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandPNGBDBM362143((S)-4-amino-6-((1-(5-chloro-3-(3-(3-ethylureido)ph...)
Affinity DataIC50: 1.80E+6nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandPNGBDBM362166((S)-3-(2-(((6-amino-5-chloropyrimidin-4-yl)amino)(...)
Affinity DataIC50: 2.40E+6nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandPNGBDBM288963(US10092563, Compound 100)
Affinity DataIC50: 9.70E+5nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288867(US10092563, Compound 2)
Affinity DataIC50: 9.50E+5nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288995(US10092563, Compound 133)
Affinity DataIC50: 9.00E+5nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288925(US10092563, Compound 62)
Affinity DataIC50: 8.20E+5nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288962(US10092563, Compound 99)
Affinity DataIC50: 7.20E+5nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288877(US10092563, Compound 12)
Affinity DataIC50: 6.60E+5nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM362066(US10221197, Compound 60 | (S)-1-(3-(2-(1-((6-amino...)
Affinity DataIC50: 6.10E+5nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandPNGBDBM288976(US10092563, Compound 113)
Affinity DataIC50: 6.00E+5nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM362064(US10221197, Compound 58 | (S)-1-(3-(2-(1-((6-amino...)
Affinity DataIC50: 5.80E+5nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandPNGBDBM288900(US10092563, Compound 35)
Affinity DataIC50: 5.70E+5nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288937(US10092563, Compound 74)
Affinity DataIC50: 5.70E+5nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288980(US10092563, Compound 117)
Affinity DataIC50: 5.70E+5nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM362060((S)-1-(3-(2-(1-((6-amino-5-cyanopyrimidin-4-yl)ami...)
Affinity DataIC50: 5.50E+5nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandPNGBDBM288974(US10092563, Compound 111)
Affinity DataIC50: 5.30E+5nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM362011(US10221197, Compound 6 | US10221197, Compound 5)
Affinity DataIC50: 5.26E+5nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

LigandPNGBDBM288944(US10092563, Compound 81)
Affinity DataIC50: 5.20E+5nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

LigandPNGBDBM288970(US10092563, Compound 107)
Affinity DataIC50: 5.20E+5nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2019
Entry Details
US Patent

Displayed 1 to 50 (of 1784 total ) | Next | Last >>
Jump to: