Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 4nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 4.20nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataKd: 4.80nMAssay Description:Binding affinity to Bap-tagged BDK (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 6nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 6.70nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human BDK using LBD-Tev-PhosphoPep/Lipoyl as substrate preincubated for 15 mins followed by substrate/ATP addition and measured after 9...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 7.40nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 7.60nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 10nMAssay Description:Inhibition of human BDK using LBD-Tev-PhosphoPep/Lipoyl as substrate preincubated for 15 mins followed by substrate/ATP addition and measured after 9...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 10nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 11nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 11nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 12nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 12.1nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 13nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 15nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 15nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 15nMAssay Description:Inhibition of human BDK using LBD-Tev-PhosphoPep/Lipoyl as substrate preincubated for 15 mins followed by substrate/ATP addition and measured after 9...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 15nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 16nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 16nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 17nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 17nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 18nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 18nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 20nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 20nMAssay Description:Inhibition of human BDK using LBD-Tev-PhosphoPep/Lipoyl as substrate preincubated for 15 mins followed by substrate/ATP addition and measured after 9...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 20nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 21nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 22nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 24nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 24nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 24nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 26nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 28nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 33nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 33nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 33nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 34nMAssay Description:Inhibition of human BDK using LBD-Tev-PhosphoPep/Lipoyl as substrate preincubated for 15 mins followed by substrate/ATP addition and measured after 9...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 34nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 36nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 37nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 41nMAssay Description:Inhibition of human BDK using LBD-Tev-PhosphoPep/Lipoyl as substrate preincubated for 15 mins followed by substrate/ATP addition and measured after 9...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 41nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 46nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 46nMAssay Description:Inhibition of BDK in human skeletal myocyte using BCKDHA as substrate assessed as inhibition of substrate phosphorylation incubated for 60 mins by Al...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 47nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 47nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 50nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair
Target[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial(Human)
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 56nMAssay Description:BCKDK activity was monitored by phosphorylation of a HIS-tagged fusion BCKDHE1α-E2 substrate protein as described above and was detected using a time...More data for this Ligand-Target Pair










































