Compile Data Set for Download or QSAR
Report error Found 41 for UniProtKB: O43741
LigandChemical structure of BindingDB Monomer ID 50195534BDBM50195534(CHEMBL3957286)
Affinity DataEC50:  4nMAssay Description:Activation of human recombinant AMPK alpha2/beta2/gamma3 expressed in African green monkey COS7 cells assessed as increase in biotinylated AAC (1 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50195534BDBM50195534(CHEMBL3957286)
Affinity DataEC50:  4nMAssay Description:Activation of human recombinant AMPK alpha1/beta2/gamma1 expressed in African green monkey COS7 cells assessed as increase in biotinylated AAC (1 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  10nMAssay Description:Binding affinity to human PRKAB2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50246120BDBM50246120(CHEMBL4082745)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human recombinant phosphorylated AMPK complex 11 alpha2/beta2/gamma2 expressed in baculovirus infected Sf21 cells assessed as pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  32nMAssay Description:Binding affinity to human PRKAB2 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50246120BDBM50246120(CHEMBL4082745)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human recombinant phosphorylated AMPK complex 12 alpha2/beta2/gamma3 expressed in baculovirus infected Sf21 cells assessed as pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50622900BDBM50622900(CHEMBL5438171)
Affinity DataIC50: 36nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50246120BDBM50246120(CHEMBL4082745)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human recombinant phosphorylated AMPK complex 4 alpha1/beta2/gamma1 expressed in baculovirus infected Sf21 cells assessed as phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50622903BDBM50622903(CHEMBL5428147)
Affinity DataIC50: 71nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50622906BDBM50622906(CHEMBL5412961)
Affinity DataIC50: 263nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50622914BDBM50622914(CHEMBL5396179)
Affinity DataIC50: 531nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50621266BDBM50621266(CHEMBL5404502)
Affinity DataIC50: 582nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50622912BDBM50622912(CHEMBL5397288)
Affinity DataIC50: 649nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50622905BDBM50622905(CHEMBL5401167)
Affinity DataIC50: 659nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50622904BDBM50622904(CHEMBL5415699)
Affinity DataIC50: 772nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50622910BDBM50622910(CHEMBL5403558)
Affinity DataIC50: 833nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50622913BDBM50622913(CHEMBL5395705)
Affinity DataIC50: 885nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50622911BDBM50622911(CHEMBL5419476)
Affinity DataIC50: 914nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50621265BDBM50621265(CHEMBL5420455)
Affinity DataIC50: 929nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50600528BDBM50600528(CHEMBL5191686)
Affinity DataEC50:  1.30E+3nMAssay Description:Activation of recombinant AMPK-beta2 (unknown origin) assessed as increase in AMPK phosphorylation by DELFIA fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50622902BDBM50622902(CHEMBL5427025)
Affinity DataIC50: 2.13E+3nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50246120BDBM50246120(CHEMBL4082745)
Affinity DataEC50:  2.86E+3nMAssay Description:Agonist activity at human recombinant phosphorylated AMPK complex 6 alpha1/beta2/gamma3 expressed in baculovirus infected Sf21 cells assessed as phos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50622901BDBM50622901(CHEMBL5430774)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50622908BDBM50622908(CHEMBL5410107)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50622909BDBM50622909(CHEMBL5431938)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of AMPK alpha1/beta2/gamma1 (unknown origin) using SAMStide as substrate incubated for 45 to 60 mins in presence of 5'AMP and ATP by [33P]...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50195479BDBM50195479(CHEMBL3950376)
Affinity DataEC50: <5.00E+3nMAssay Description:Activation of human recombinant AMPK beta2 expressed in African green monkey COS7 cells or baculovirus infected insect cells assessed as increase in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50242401BDBM50242401(A-769662 | 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-6...)
Affinity DataKd:  1.45E+4nMAssay Description:Binding affinity to human recombinant N-terminal AVI-tagged phosphorylated AMPK alpha1beta2gamma1 expressed in Escherichia coli BL21 cells after 1 to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50463099BDBM50463099(CHEMBL4246000)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50244667BDBM50244667(CHEMBL4105032)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50463100BDBM50463100(CHEMBL4249790)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 238079BDBM238079(US9394285, 173)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha1beta2gamma1 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50244667BDBM50244667(CHEMBL4105032)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha1beta2gamma1 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 237920BDBM237920(US9394285, 1)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of recombinant human AMPK alpha1/beta2/gamma1 using Cy5-labelled SAMS as substrate in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50463101BDBM50463101(CHEMBL4250253)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha1beta2gamma1 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 237920BDBM237920(US9394285, 1)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of recombinant human AMPK alpha2/beta2/gamma3 by using Cy5-labelled SAMS as substrate in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 237920BDBM237920(US9394285, 1)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50463101BDBM50463101(CHEMBL4250253)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50463100BDBM50463100(CHEMBL4249790)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha1beta2gamma1 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 237920BDBM237920(US9394285, 1)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha1beta2gamma1 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50463099BDBM50463099(CHEMBL4246000)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha1beta2gamma1 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 238079BDBM238079(US9394285, 173)
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed