Compile Data Set for Download or QSAR
Report error Found 1944 for UniProtKB: O95180
LigandChemical structure of BindingDB Monomer ID 363976BDBM363976(US9856250, 11 | N-[(exo)-8-(tert-Butylcarbamoyl)me...)
Affinity DataIC50: 3nMAssay Description:The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50452243BDBM50452243(CHEMBL4205005)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452233BDBM50452233(CHEMBL4203101)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50322938BDBM50322938(2-(3-chloro-4-fluorophenyl)-N-(3,5-difluorophenyl)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50322938BDBM50322938(2-(3-chloro-4-fluorophenyl)-N-(3,5-difluorophenyl)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human CaV3.2 expressed in HEK293 cells at -100 mV membrane potential by Ionworks HT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452301BDBM50452301(CHEMBL4204077)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452289BDBM50452289(CHEMBL4215974)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452236BDBM50452236(CHEMBL4204507)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452256BDBM50452256(CHEMBL4212039)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50200910BDBM50200910(CHEMBL3906825)
Affinity DataIC50: 6nMAssay Description:Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452294BDBM50452294(CHEMBL4207031)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452242BDBM50452242(CHEMBL4206509)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 372453BDBM372453(US10246426, Example 7 | N-[2-(3,4-Difluoro-benzyl)...)
Affinity DataIC50: 6.40nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50451717BDBM50451717(CHEMBL4202587)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of recombinant human Cav3.2 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452323BDBM50452323(CHEMBL4214862)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452258BDBM50452258(CHEMBL4208907)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 372463BDBM372463(US10246426, Example 17 | N-[2-(3,4-Difluoro-benzyl...)
Affinity DataIC50: 7.30nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 372533BDBM372533(US10246426, Example 91 | 2-(1-Methyl-1H-indol-5-yl...)
Affinity DataIC50: 7.40nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50452303BDBM50452303(CHEMBL4218608)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452238BDBM50452238(CHEMBL4207291)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452246BDBM50452246(CHEMBL4216687)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50192668BDBM50192668(CHEMBL1684950 | US20240190865, Example 56)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human T-type calcium channel Cav3.2 expressed in CHO cells assessed as inhibition of calcium tail current at -90 mV holding potential m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50192668BDBM50192668(CHEMBL1684950 | US20240190865, Example 56)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of CaV 3.2 channel (unknown origin) expressed in HEK293 cells by FLEPR Ca2+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452305BDBM50452305(CHEMBL4203847)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 372452BDBM372452(US10246426, Example 6 | N-[2-(3,4-Difluoro-benzyl)...)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 372629BDBM372629(N-[2-(3-Fluoro-4-trifluoromethoxy-benzyl)-2H-[1,2,...)
Affinity DataIC50: 8.80nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50200787BDBM50200787(CHEMBL3906199)
Affinity DataIC50: 9nMAssay Description:Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 372452BDBM372452(US10246426, Example 6 | N-[2-(3,4-Difluoro-benzyl)...)
Affinity DataIC50: 9.5nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 372465BDBM372465(US10246426, Example 19 | N-[2-(3,4-Difluoro-benzyl...)
Affinity DataIC50: 9.70nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 372473BDBM372473(US10246426, Example 27 | N-[2-(3,4-Difluoro-benzyl...)
Affinity DataIC50: 9.80nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 372534BDBM372534(US10246426, Example 92 | 2-(1-Methyl-1H-indazol-5-...)
Affinity DataIC50: 9.90nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50452229BDBM50452229(CHEMBL4209376)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 364007BDBM364007(US9856250, 84)
Affinity DataIC50: 10nMAssay Description:The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 372536BDBM372536(US10246426, Example 94 | 2-[6-(3,3-Difluoro-pyrrol...)
Affinity DataIC50: 10nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50452269BDBM50452269(CHEMBL4213335)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452225BDBM50452225(CHEMBL4203748)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50200898BDBM50200898(CHEMBL3924174)
Affinity DataIC50: 11nMAssay Description:Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452306BDBM50452306(CHEMBL4211105)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 372637BDBM372637(2-(1,3-Dimethyl-1H-indazol-5-yl)-N-[2-(3-fluoro-4-...)
Affinity DataIC50: 11nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 372477BDBM372477(US10246426, Example 31 | N-[2-(3,4-Difluoro-benzyl...)
Affinity DataIC50: 11nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 372496BDBM372496(US10246426, Example 52 | N-[2-(4-Fluoro-benzyl)-2H...)
Affinity DataIC50: 12nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50452325BDBM50452325(CHEMBL4208950)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50451723BDBM50451723(CHEMBL4205453)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human Cav3.2 expressed in HEK293 cells assessed as reduction in CaCl2-induced intracellular calcium flux incubated for 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50200904BDBM50200904(CHEMBL3936835)
Affinity DataIC50: 12nMAssay Description:Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50452288BDBM50452288(CHEMBL4208626)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 372521BDBM372521(US10246426, Example 77 | N-[2-(3,5-Difluoro-4-meth...)
Affinity DataIC50: 13nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50200851BDBM50200851(CHEMBL3969822)
Affinity DataIC50: 13nMAssay Description:Channel blocking activity at recombinant human CaV 3.2 channel expressed in HEK293 cells assessed as inhibition of Ca2+ flux preincubated for 3 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2018
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 372622BDBM372622(N-[2-(4-Difluoromethoxy-3-fluoro-benzyl)-2H-[1,2,3...)
Affinity DataIC50: 13nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 372588BDBM372588(US10246426, Example 147 | N-[2-(3,5-Difluoro-4-met...)
Affinity DataIC50: 13nMAssay Description:Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 364014BDBM364014(US9856250, 104 | 3-Chloro-5-fluoro-N-{(exo)-8-[(2-...)
Affinity DataIC50: 13nMAssay Description:The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent

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