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Report error Found 10 for UniProtKB: O95563
TargetMitochondrial pyruvate carrier 2(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466687BDBM50466687(CHEMBL4291468)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of photoprobe from MPC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitochondrial pyruvate carrier 2(Human)
Sptanis Pharmachem Consulting

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 228129BDBM228129(US9562012, mitoglitazone)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of photoprobe from MPC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitochondrial pyruvate carrier 1/2(Human)
Minoryx Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 723998BDBM723998(US20250064791, Compound Rosiglitazone)
Affinity DataIC50: 2.00E+3nMAssay Description:The MPC is a heterodimer composed of two subunits, MPC1 and MPC2. MPC1 and MPC2 interact to form an active carrier. In the assay, MPC2 was fused to R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/29/2025
Entry Details
US Patent

TargetMitochondrial pyruvate carrier 1/2(Human)
Minoryx Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50030474BDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataIC50: 2.00E+3nMAssay Description:The MPC is a heterodimer composed of two subunits, MPC1 and MPC2. MPC1 and MPC2 interact to form an active carrier. In the assay, MPC2 was fused to R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetMitochondrial pyruvate carrier 1/2(Human)
Minoryx Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50530214BDBM50530214(CHEBI:82937 | Leriglitazone | Min-102 | US20240091...)
Affinity DataIC50: 4.10E+3nMAssay Description:The MPC is a heterodimer composed of two subunits, MPC1 and MPC2. MPC1 and MPC2 interact to form an active carrier. In the assay, MPC2 was fused to R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2025
Entry Details
US Patent

TargetMitochondrial pyruvate carrier 1/2(Human)
Minoryx Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50530214BDBM50530214(CHEBI:82937 | Leriglitazone | Min-102 | US20240091...)
Affinity DataIC50: 4.10E+3nMAssay Description:The MPC is a heterodimer composed of two subunits, MPC1 and MPC2. MPC1 and MPC2 interact to form an active carrier. In the assay, MPC2 was fused to R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetMitochondrial pyruvate carrier 1/2(Human)
Minoryx Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 723999BDBM723999(US20250064791, Compound UK5099)
Affinity DataIC50: 1.70E+4nMAssay Description:The MPC is a heterodimer composed of two subunits, MPC1 and MPC2. MPC1 and MPC2 interact to form an active carrier. In the assay, MPC2 was fused to R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/29/2025
Entry Details
US Patent

TargetMitochondrial pyruvate carrier 1/2(Human)
Minoryx Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50608638BDBM50608638(CHEMBL4303684 | US20240091210, Compound UK5099)
Affinity DataIC50: 1.70E+4nMAssay Description:The MPC is a heterodimer composed of two subunits, MPC1 and MPC2. MPC1 and MPC2 interact to form an active carrier. In the assay, MPC2 was fused to R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent

TargetMitochondrial pyruvate carrier 1/2(Human)
Minoryx Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 724000BDBM724000(US20250064791, Compound Pioglitazone)
Affinity DataIC50: 1.00E+5nMAssay Description:The MPC is a heterodimer composed of two subunits, MPC1 and MPC2. MPC1 and MPC2 interact to form an active carrier. In the assay, MPC2 was fused to R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/29/2025
Entry Details
US Patent

TargetMitochondrial pyruvate carrier 1/2(Human)
Minoryx Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50103521BDBM50103521(CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...)
Affinity DataIC50: 1.00E+5nMAssay Description:The MPC is a heterodimer composed of two subunits, MPC1 and MPC2. MPC1 and MPC2 interact to form an active carrier. In the assay, MPC2 was fused to R...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
US Patent