Compile Data Set for Download or QSAR
maximum 50k data
Found 17 of affinity data for UniProtKB/TrEMBL: P04792
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50263167(3,4,5,6-Tetrahydro-2H-[1,2']bipyridinyl-4'-carboxy...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50263168(CHEMBL476351 | N-[4'-(Cyclopropylmethyl-carbamoyl)...)
Affinity DataIC50:  27nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50263093(6-Methyl-biphenyl-3,4'-dicarboxylic acid 3-cyclopr...)
Affinity DataIC50:  53nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  58nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262865(CHEMBL477583 | Furan-3-carboxylic acid [4'-(cyclop...)
Affinity DataIC50:  88nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM15458(4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidaz...)
Affinity DataIC50:  160nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097558(CHEMBL1935538 | NSC-751382)
Affinity DataIC50:  200nMAssay Description:Inhibition of HSP27 (unknown origin) by insulin aggregation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50559487(CHEMBL4755850)
Affinity DataKd:  6.30E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50559488(CHEMBL1562220)
Affinity DataKd:  1.77E+5nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50559486(CHEMBL4777949)
Affinity DataKd:  6.40E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50559485(CHEMBL4787246)
Affinity DataKd:  6.80E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50559484(CHEMBL4784519)
Affinity DataKd:  2.20E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50559483(CHEMBL4784495)
Affinity DataKd:  4.70E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50559482(CHEMBL4761994)
Affinity DataKd:  8.00E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50559489(CHEMBL1608020)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50559480(CHEMBL4760956)
Affinity DataKd:  7.00E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50559481(CHEMBL4799413)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed