Compile Data Set for Download or QSAR
Report error Found 1118 of affinity data for UniProtKB/TrEMBL: P05164
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50554035BDBM50554035(CHEMBL4790231)
Affinity DataIC50: 1nMAssay Description:Inhibition of MPO (unknown origin) chlorination activity incubated for 10 mins followed by NaCl addition by aminophenyl fluorescein assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676534BDBM676534(US20240166642, Example 19b)
Affinity DataIC50: 1nMAssay Description:Inhibition of human MPO using H2O2 as substrate measured after 15 mins by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50554034BDBM50554034(CHEMBL4747269)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676534BDBM676534(US20240166642, Example 19b)
Affinity DataIC50: 1.30nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50554035BDBM50554035(CHEMBL4790231)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676519BDBM676519(US20240166642, Example 10b)
Affinity DataIC50: 1.5nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312172BDBM312172(Alternative Preparation | US9616063, 3 | US1001643...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of MPO (unknown origin) measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312172BDBM312172(Alternative Preparation | US9616063, 3 | US1001643...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of MPO (unknown origin) measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676524BDBM676524(US20240166642, Example 13b)
Affinity DataIC50: 2nMAssay Description:Inhibition of human MPO using H2O2 as substrate measured after 15 mins by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50554052BDBM50554052(CHEMBL4763667)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676519BDBM676519(US20240166642, Example 10b)
Affinity DataIC50: 2nMAssay Description:Inhibition of human MPO using H2O2 as substrate measured after 15 mins by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676505BDBM676505(US20240166642, Example 1b)
Affinity DataIC50: 2nMAssay Description:Inhibition of human MPO using H2O2 as substrate measured after 15 mins by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676505BDBM676505(US20240166642, Example 1b)
Affinity DataIC50: 2.10nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676524BDBM676524(US20240166642, Example 13b)
Affinity DataIC50: 2.30nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676522BDBM676522(US20240166642, Example 12b)
Affinity DataIC50: 2.70nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676532BDBM676532(US20240166642, Example 18b)
Affinity DataIC50: 2.70nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676514BDBM676514(US20240166642, Example 6b)
Affinity DataIC50: 2.80nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50554050BDBM50554050(CHEMBL4752248)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676532BDBM676532(US20240166642, Example 18b)
Affinity DataIC50: 3nMAssay Description:Inhibition of human MPO using H2O2 as substrate measured after 15 mins by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676522BDBM676522(US20240166642, Example 12b)
Affinity DataIC50: 3nMAssay Description:Inhibition of human MPO using H2O2 as substrate measured after 15 mins by chemiluminescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676543BDBM676543(US20240166642, Example 28)
Affinity DataIC50: 3nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432573BDBM50432573(CHEMBL2347170)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676508BDBM676508(US20240166642, Example 3a)
Affinity DataIC50: 3nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676530BDBM676530(US20240166642, Example 17b)
Affinity DataIC50: 3.40nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676507BDBM676507(US20240166642, Example 2b)
Affinity DataIC50: 3.60nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50595667BDBM50595667(CHEMBL5181350)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of MPO (unknown origin) measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676528BDBM676528(US20240166642, Example 16b)
Affinity DataIC50: 3.90nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432575BDBM50432575(CHEMBL2347168)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507392BDBM50507392(CHEMBL4548537 | US10981879, Example 11)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human PMN leukocytes MPO peroxidation activity using H2O2 as substrate preincubated for 10 mins followed by H2O2 addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332590BDBM50332590(5-(5-fluoro-1H-indol-3-yl)pentan-1-amine | CHEMBL1...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant MPO mediated LDL oxidation using MPO/Cl-/H2O2 systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50595661BDBM50595661(CHEMBL5197968)
Affinity DataIC50: 5nMAssay Description:Inhibition of MPO (unknown origin) measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50554057BDBM50554057(CHEMBL4740830)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50595661BDBM50595661(CHEMBL5197968)
Affinity DataIC50: 5nMAssay Description:Inhibition of MPO (unknown origin) measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238843BDBM50238843(CHEMBL4068067)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676542BDBM676542(US20240166642, Example 27)
Affinity DataIC50: 5nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332590BDBM50332590(5-(5-fluoro-1H-indol-3-yl)pentan-1-amine | CHEMBL1...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432568BDBM50432568(CHEMBL2347177)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 434866BDBM434866(US10577383, Example 26 | 7-[(3R,4S,6S,10R)-4-Benzy...)
Affinity DataIC50: 5nMAssay Description:Inhibition of MPO (unknown origin) chlorination activity incubated for 10 mins followed by NaCl addition by aminophenyl fluorescein assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 217354BDBM217354(2-(3,5-bistrifluoromethylbenzylamino)-6-oxo-1H-pyr...)
Affinity DataIC50: 5.01nMpH: 6.5Assay Description:Assays were performed at 22 °C with 2 nM MPO and 10 μM hydrogen peroxide (H2O2) in 20 mM NaH2PO4 buffer, pH 6.5 containing 140 mM NaCl, 10 mM ta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676536BDBM676536(US20240166642, Example 21)
Affinity DataIC50: 5.70nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50554056BDBM50554056(CHEMBL4782307)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 120 mM NaCl by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432573BDBM50432573(CHEMBL2347170)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 676518BDBM676518(US20240166642, Example 10a)
Affinity DataIC50: 6nMAssay Description:The experiments were performed in phosphate-buffered saline (PBS), pH7.4. A 10 mM luminol (A4695, Sigma Aldrich, St Louis, MO, USA) stock was prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50432580BDBM50432580(CHEMBL2347032)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507396BDBM50507396(CHEMBL4453728)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human PMN leukocytes MPO peroxidation activity using H2O2 as substrate preincubated for 10 mins followed by H2O2 addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507390BDBM50507390(CHEMBL4482878 | US10981879, Example 3)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human PMN leukocytes MPO chlorination activity using H2O2 as substrate preincubated for 10 mins followed by H2O2 addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312172BDBM312172(Alternative Preparation | US9616063, 3 | US1001643...)
Affinity DataIC50: 7nMAssay Description:The pharmacological activity of compounds disclosed herein was tested in the following screen (Test A) in which the compounds were tested in the pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312172BDBM312172(Alternative Preparation | US9616063, 3 | US1001643...)
Affinity DataIC50: 7nMAssay Description:Methods for the determination of MPO inhibitory activity are disclosed in WO 02/090575. The pharmacological activity of compounds disclosed herein wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312171BDBM312171(1-[2-(1-Aminoethyl)-4-chlorobenzyl]-2-thioxo-1,2,3...)
Affinity DataIC50: 7nMAssay Description:Methods for the determination of MPO inhibitory activity are disclosed in WO 02/090575. The pharmacological activity of compounds disclosed herein wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312171BDBM312171(1-[2-(1-Aminoethyl)-4-chlorobenzyl]-2-thioxo-1,2,3...)
Affinity DataIC50: 7nMAssay Description:MPO: The pharmacological activity of compounds disclosed herein was tested in the following screen (Test A) in which the compounds were tested in the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

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