Compile Data Set for Download or QSAR
maximum 50k data
Found 248 for UniProtKB: P05412
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50135483(1-(6-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...)
Affinity DataIC50:  3nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50135482(1-(5-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50092879(2-Chloro-4-methyl-pyrimidine-5-carboxylic acid (3,...)
Affinity DataIC50:  20nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090430(4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...)
Affinity DataIC50:  20nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50092879(2-Chloro-4-methyl-pyrimidine-5-carboxylic acid (3,...)
Affinity DataIC50:  20nMAssay Description:Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50090430(4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...)
Affinity DataIC50:  20nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50340608(8-(6-methylpyridin-3-yl)-N-(4-(3-morpholino-1H-1,2...)
Affinity DataIC50:  20nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50295171(AILANTHINONE | CHEMBL487194)
Affinity DataIC50:  32nMAssay Description:Inhibition of TPA-induced AP1 transfected in HEK293 cells assessed as inhibition of beta-lactamase reporter activity treated 1 hr before TPA stimulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50044568(CHEMBL85822)
Affinity DataIC50:  35nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50340627(7,8-bis(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholi...)
Affinity DataIC50:  40nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50349194(GLAUCARUBINONE | NSC-14975)
Affinity DataIC50:  40nMAssay Description:Inhibition of TPA-induced AP1 transfected in HEK293 cells assessed as inhibition of beta-lactamase reporter activity treated 1 hr before TPA stimulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50340628(7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morpholino-1H...)
Affinity DataIC50:  40nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50340606(CHEMBL1761561 | N-(4-(3-(6-methylpyridin-3-yl)-1H-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50044567(CHEMBL86615)
Affinity DataIC50:  45nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50062648(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Affinity DataIC50:  50nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50062648(2-Chloro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Affinity DataIC50:  50nMAssay Description:Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50340629(8-methoxy-7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-mor...)
Affinity DataIC50:  50nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50213931(CHEMBL250854 | tylophorinidine)
Affinity DataIC50:  65nMAssay Description:Inhibition of AP1-mediated gene transcription in HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50213932(CHEMBL250474 | [(R)-(+)-deoxytylophorinidine)
Affinity DataIC50:  68nMAssay Description:Inhibition of AP1-mediated gene transcription in HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50295170(6R-senecionylchaparrin | CHEMBL564009)
Affinity DataIC50:  71nMAssay Description:Inhibition of TPA-induced AP1 transfected in HEK293 cells assessed as inhibition of beta-lactamase reporter activity treated 1 hr before TPA stimulat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50044564(CHEMBL315804)
Affinity DataIC50:  98nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50092877(2-Fluoro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Affinity DataIC50:  100nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50092877(2-Fluoro-4-trifluoromethyl-pyrimidine-5-carboxylic...)
Affinity DataIC50:  100nMAssay Description:Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090407(4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...)
Affinity DataIC50:  100nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50340622(8-chloro-7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morp...)
Affinity DataIC50:  100nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50044572(CHEMBL3341912)
Affinity DataIC50:  100nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50090444(4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...)
Affinity DataIC50:  100nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090444(4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...)
Affinity DataIC50:  100nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50213934(CHEMBL398325 | tylophorinine)
Affinity DataIC50:  110nMAssay Description:Inhibition of AP1-mediated gene transcription in HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50340600(CHEMBL1761555 | N-(4-(3-morpholino-1H-1,2,4-triazo...)
Affinity DataIC50:  120nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50340626(8-cyclopropyl-7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3...)
Affinity DataIC50:  130nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50340624(8-methyl-7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-morp...)
Affinity DataIC50:  160nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090442(3-Methyl-1-[5-(2-methyl-2H-tetrazol-5-yl)-2-thioph...)
Affinity DataIC50:  200nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50092882(2,4-Dichloro-pyrimidine-5-carboxylic acid (3,5-bis...)
Affinity DataIC50:  200nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090443(4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...)
Affinity DataIC50:  200nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50340614(CHEMBL1761569 | N-(4-(3-methyl-1H-1,2,4-triazol-1-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090420(4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...)
Affinity DataIC50:  200nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090431(3-Methyl-1-[5-(4-methyl-oxazol-2-yl)-2-thiophen-2-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090406(1-(5-(4,5-dihydrooxazol-2-yl)-2-(thiophen-2-yl)pyr...)
Affinity DataIC50:  200nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50092882(2,4-Dichloro-pyrimidine-5-carboxylic acid (3,5-bis...)
Affinity DataIC50:  200nMAssay Description:Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50044566(CHEMBL87274)
Affinity DataIC50:  210nMAssay Description:Inhibition of AP-1-mediated transcriptional activation in human Jurkat cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50340610(8-(3-fluoro-4-methoxyphenyl)-N-(4-(3-morpholino-1H...)
Affinity DataIC50:  250nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50340607(7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-(pyridin-2-yl...)
Affinity DataIC50:  290nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090435(3-Methyl-1-[5-(3-methyl-isoxazol-5-yl)-2-thiophen-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090450(3-Methyl-1-[5-(5-methyl-[1,3,4]oxadiazol-2-yl)-2-t...)
Affinity DataIC50:  300nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50213936((S)-2,3,6,7-tetramethoxy-8b,9,10,11,12,12a-hexahyd...)
Affinity DataIC50: >300nMAssay Description:Inhibition of AP1-mediated gene transcription in HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090433(2-(5-Chloro-thiophen-2-yl)-4-(3-methyl-2,5-dioxo-2...)
Affinity DataIC50:  300nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50213935((12aS,13R)-2,3,6,7-tetramethoxy-9,10,11,12,12a,13-...)
Affinity DataIC50: >300nMAssay Description:Inhibition of AP1-mediated gene transcription in HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50092890(2-Chloro-pyrimidine-5-carboxylic acid (3,5-bis-tri...)
Affinity DataIC50:  300nMAssay Description:Concentration required to inhibit activator protein-1(AP-1) mediated transcriptional activation in human Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein c-Fos/Transcription factor Jun(Homo sapiens (Human))
Signal Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090429(2-(3,5-Dichloro-phenyl)-4-(3-methyl-2,5-dioxo-2,5-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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