TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.253nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:Inhibition of Escherichia coli DNA gyrase using fluorescence-tagged DNA by fluorescenct polarization assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.310nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.360nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.380nMAssay Description:Inhibition of Escherichia coli DNA gyrase using fluorescence-tagged DNA by fluorescenct polarization assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.430nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.520nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.530nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.570nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.660nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.770nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Escherichia coli DNA gyrase incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.940nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 0.950nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Escherichia coli DNA gyrase by isothermal titration calorimetry (ITC) assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of BACE1 by cell-based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of BACE1 assessed as amyloid beta secretion by cell based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activity by Microplate Assay kit methodMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Escherichia coli DNA gyraseMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Ligand Info
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Escherichia coli DNA gyrase incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Ligand Info
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Queensland University of Technology
Curated by ChEMBL
Queensland University of Technology
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activity by Microplate Assay kit methodMore data for this Ligand-Target Pair













3D Structure (crystal)

































