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TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193784(US9670209, Compound 302 1-((R)-3-((1R,3R,5S)-3-(cy...)
Affinity DataEC50:  1.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193784(US9670209, Compound 302 1-((R)-3-((1R,3R,5S)-3-(cy...)
Affinity DataEC50:  3.20nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193785(US9670209, Compound 303 1-((R)-3-((1R,3R,5S)-3-(2-...)
Affinity DataEC50:  4nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193787(US9670209, Compound 304 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  1.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193787(US9670209, Compound 304 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  5nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193788(US9670209, Compound 305 1-((R)-3-((1R,3R,5S)-3-(Al...)
Affinity DataEC50:  7.90nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193789(US9670209, Compound 307 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  0.320nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193789(US9670209, Compound 307 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  10nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193790(US9670209, Compound 308 1-((R)-3-(3-(Allyloxy)-8-a...)
Affinity DataEC50:  1.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193790(US9670209, Compound 308 1-((R)-3-(3-(Allyloxy)-8-a...)
Affinity DataEC50:  79nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193791(US9670209, Compound 309 1-((R)-3-(3-(2-Methoxyethy...)
Affinity DataEC50:  0.400nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193791(US9670209, Compound 309 1-((R)-3-(3-(2-Methoxyethy...)
Affinity DataEC50:  50nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193795(US9670209, Compound 310 1-((R)-3-((1R,3R,5S)-3-(cy...)
Affinity DataEC50:  32nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193800(US9670209, Compound 311 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  10nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193802(US9670209, Compound 312 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  0.5nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193802(US9670209, Compound 312 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  13nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193803(US9670209, Compound 313 1-((R)-3-((1R,3R,58)-3-(2-...)
Affinity DataEC50:  6.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193804(US9670209, Compound 314 1-((R)-3-((1R,3R,58)-3-(cy...)
Affinity DataEC50:  4nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193805(US9670209, Compound 315 1-((R)-3-(3-(cyclobutylmet...)
Affinity DataEC50:  7.90nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193806(US9670209, Compound 316 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  13nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193807(US9670209, Compound 317 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  25nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193808(US9670209, Compound 318 1-((R)-3-((1R,3R,5S)-3-(pr...)
Affinity DataEC50:  10nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193815(US9670209, Compound 319 1-((R)-3-(3-(propoxy)-8-az...)
Affinity DataEC50:  7.90nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193818(US9670209, Compound 320 1-((R)-3-((1R,3R,58)-3-(2-...)
Affinity DataEC50:  6.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193819(US9670209, Compound 321 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  13nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193820(US9670209, Compound 322 1-((R)-3-((1R,3R,5S)-3-(pr...)
Affinity DataEC50:  10nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193823(US9670209, Compound 323 1-((R)-3-((1R,3R,5S)-3-(2-...)
Affinity DataEC50:  0.790nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193825(US9670209, Compound 324 1-((R)-3-((1R,3R,5S)-3-(2-...)
Affinity DataEC50:  0.790nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193787(US9670209, Compound 304 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  1.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193787(US9670209, Compound 304 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  5nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193788(US9670209, Compound 305 1-((R)-3-((1R,3R,5S)-3-(Al...)
Affinity DataEC50:  7.90nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataEC50:  1.60E+3nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM50396483(PLX-4032 | RG 7204 | Ro 5185426 | VEMURAFENIB | US...)
Affinity DataEC50:  790nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193834(US9670209, Comparative compound 2)
Affinity DataEC50:  1nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193834(US9670209, Comparative compound 2)
Affinity DataEC50:  13nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261715(US9708302, 3 | 4-((6-Chloropyridin-3-yl)methyl)-1-...)
Affinity DataEC50:  159nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261716(4-((6-chloropyridin-3- yl)methyl)-1-fluoro-N- ((3R...)
Affinity DataEC50:  53nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261715(US9708302, 3 | 4-((6-Chloropyridin-3-yl)methyl)-1-...)
Affinity DataEC50:  84nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261718(4-((6-Chloropyridin-3-yl)methyl)-1-fluoro-N-((3S,4...)
Affinity DataEC50:  428nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261719(4-((6-chloropyridin-3- yl)methyl)-1-fluoro-N- ((1S...)
Affinity DataEC50:  363nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261720(4-((6-chloropydridin-3- yl)methyl)-1-fluoro-N-((1S...)
Affinity DataEC50:  575nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261721(4-((6-chloropyridin-3- yl)methyl)-1-fluoro-N- ((1S...)
Affinity DataEC50:  561nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261722(4-((6-chloropyridin-3- yl)methyl)-1-fluoro-N- ((1S...)
Affinity DataEC50:  524nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261723(4-((6-chloropyridin-3- yl)methyl)-1-fluoro-N- ((1S...)
Affinity DataEC50:  539nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261724(1-Fluoro-N-((3RS,4SR)-3-hydroxytetrahydro-2H-pyran...)
Affinity DataEC50:  154nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261725(4-benzyl-1-fluoro-N- ((3RS,4SR)-3- hydroxytetrahyd...)
Affinity DataEC50:  197nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261726(4-(4-chlorobenzyl)- 1-fluoro-N- ((3RS,4SR)-3- hydr...)
Affinity DataEC50:  152nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261727(4-(4-cyanobenzyl)- 1-fluoro-N- ((3RS,4SR)-3- hydro...)
Affinity DataEC50:  67nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261728(1-fluoro-4-(2-fluoro- 4-(1-methyl-1H- pyrazol-4- y...)
Affinity DataEC50:  14nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M1(Human)
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM261729(1-fluoro-N- ((3RS,4SR)-3- hydroxytetrahydro- 2H-py...)
Affinity DataEC50:  541nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent

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