Compile Data Set for Download or QSAR
maximum 50k data
Found 15 of affinity data for UniProtKB/TrEMBL: P13100
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18771((2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-...)
Affinity DataKi:  240nM ΔG°:  -37.2kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM50443313(CHEMBL3088233)
Affinity DataKi:  310nMAssay Description:Inhibition of Pneumocystis carinii thymidylate synthase using MTHF and dUMP as substratesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM50443314(CHEMBL3088232)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of Pneumocystis carinii thymidylate synthase using MTHF and dUMP as substratesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM50443306(CHEMBL3088242)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of Pneumocystis carinii thymidylate synthase using MTHF and dUMP as substratesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18763(1,8-naphthalein derivative, 10 | 4,4-bis(3-chloro-...)
Affinity DataKi:  1.30E+4nM ΔG°:  -27.4kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM50443309(CHEMBL3088237)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of Pneumocystis carinii thymidylate synthase using MTHF and dUMP as substratesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM50443308(CHEMBL3088238)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of Pneumocystis carinii thymidylate synthase using MTHF and dUMP as substratesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM50443310(CHEMBL3088236)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of Pneumocystis carinii thymidylate synthase using MTHF and dUMP as substratesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18770(1,8-naphthalein derivative, 18 | 8-chloro-4,4-bis(...)
Affinity DataKi:  2.20E+4nM ΔG°:  -26.1kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18753(4,4-bis(3-bromo-4-hydroxyphenyl)-10-chloro-3-oxatr...)
Affinity DataKi:  2.80E+4nM ΔG°:  -25.6kJ/molepH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18772(1,8-naphthalein derivative, 16 | 4,4-bis(3-bromo-4...)
Affinity DataKi:  2.80E+4nM ΔG°:  -25.6kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18759(1,2-naphthalein derivative, 5 | 3,3-bis(3,5-dibrom...)
Affinity DataKi:  3.27E+4nM ΔG°:  -25.2kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM50443311(CHEMBL3088235)
Affinity DataKi:  3.40E+4nMAssay Description:Inhibition of Pneumocystis carinii thymidylate synthase using MTHF and dUMP as substratesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18758(1,2-naphthalein derivative, 4 | 3,3-bis(3-bromo-4-...)
Affinity DataKi: >1.32E+5nM ΔG°: >-21.8kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Pneumocystis carinii)
UniversitÀ

LigandPNGBDBM18769(1,8-naphthalein derivative, 17 | 4,4-bis(3-fluoro-...)
Affinity DataKi: >4.02E+5nM ΔG°: >-19.1kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed