Affinity DataIC50: 720nMAssay Description:Inhibition of IL1R in TLR null HEK-blue cells assessed as decrease in IL-1beta-stimulated NF-kappaB activation-mediated SEAP production after 24 hrs ...More data for this Ligand-Target Pair
Affinity DataIC50: >6.50E+3nMAssay Description:Antagonist activity at IL1R in human PBMC assessed as inhibition of IL1beta-induced TNFalpha production preincubated for 30 mins followed by IL1beta ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of IL1R in human monocytes assessed as reduction in IL1beta-induced TNFalpha productionMore data for this Ligand-Target Pair