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TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  230nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM26300(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)
Affinity DataKd:  8.50E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd:  3.30E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM26474(GW-786034 | JMC514632 Compound 13 | 5-({4-[(2,3-di...)
Affinity DataKd:  150nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  190nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31094(PKC-412 | cid_24202429)
Affinity DataKd:  350nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataKd:  1.60E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13531(4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-...)
Affinity DataKd:  4.50E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13336(4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...)
Affinity DataKd:  2.50E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  180nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd:  3.50E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  61nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  63nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50511478(CHEMBL4519003)
Affinity DataKd: >1.00E+3nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system after 1 hr by Kinomescan meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM253941(US9464092, GG | US9527857, GG)
Affinity DataKd:  4.20nMAssay Description:Binding affinity to TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50234187(CHEMBL4093766)
Affinity DataKd:  190nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569964(CHEMBL4856340)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569965(CHEMBL4860644)
Affinity DataKd: >310nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569966(CHEMBL4855669)
Affinity DataKd:  250nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569967(CHEMBL4849289)
Affinity DataKd:  200nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569968(CHEMBL4859127)
Affinity DataKd:  9.30nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569969(CHEMBL4857210)
Affinity DataKd:  0.710nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569970(CHEMBL4850608)
Affinity DataKd:  2.80nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569971(CHEMBL4869142)
Affinity DataKd:  0.630nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569972(CHEMBL4853778)
Affinity DataKd:  4.20nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569973(CHEMBL4863607)
Affinity DataKd:  3.90nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569974(CHEMBL4861308)
Affinity DataKd:  0.720nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569975(CHEMBL4860430)
Affinity DataKd:  0.410nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569976(CHEMBL4867504)
Affinity DataKd:  0.5nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569977(CHEMBL4846040)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569978(CHEMBL4845775)
Affinity DataKd:  0.120nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569979(CHEMBL4875028)
Affinity DataKd:  0.150nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569980(CHEMBL4873395)
Affinity DataKd:  0.560nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569981(CHEMBL4868353)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569982(CHEMBL4859914)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569983(CHEMBL4870731)
Affinity DataKd:  6.10nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569984(CHEMBL4866294)
Affinity DataKd:  0.410nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569985(CHEMBL4874692)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569986(CHEMBL4853433)
Affinity DataKd:  7.90nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569987(CHEMBL4862196)
Affinity DataKd:  825nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569988(CHEMBL4869527)
Affinity DataKd:  0.290nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569989(CHEMBL4870223)
Affinity DataKd:  0.170nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569990(CHEMBL4858486)
Affinity DataKd:  0.170nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569991(CHEMBL4877547)
Affinity DataKd:  0.0710nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569992(CHEMBL4853927)
Affinity DataKd:  145nMAssay Description:Binding affinity to wild-type human partial length TTK (N505 to V798 residues) expressed in bacterial expression system by active site-directed compe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50579637(CHEMBL4878958)
Affinity DataKd:  0.900nMAssay Description:Binding affinity to TTK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50569969(CHEMBL4857210)
Affinity DataKd:  0.700nMAssay Description:Binding affinity to human TTK expressed in bacterial expression system assessed as dissociation constant at 100 nM by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50024294(SP-600125)
Affinity DataKd:  98nMAssay Description:Average Binding Constant for TTK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  100nMAssay Description:Average Binding Constant for TTK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  230nMAssay Description:Average Binding Constant for TTK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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