Compile Data Set for Download or QSAR
Report error Found 1443 of affinity data for UniProtKB/TrEMBL: Q02763
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM21079(1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...)
Affinity DataKd:  450nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  19nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM26300(cid_16007391 | 2-{3-[(7-{3-[ethyl(2-hydroxyethyl)a...)
Affinity DataKd:  1.90E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd:  20nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31088(1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-...)
Affinity DataKd:  1.30E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  950nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataKd:  300nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31094(PKC-412 | cid_24202429)
Affinity DataKd:  1.90E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd:  2.10E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  140nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  450nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM21(VANDETANIB | N-(4-bromo-2-fluorophenyl)-6-methoxy-...)
Affinity DataKd:  1.00E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM124970(US8765747, 2)
Affinity DataKd:  57nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
Go to US Patent

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50105763(Ethyl-{4-[5-(4-fluoro-phenyl)-3-(1-methyl-piperidi...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM586640(D3RKN_29)
Affinity DataKd:  3.40nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50349213(CHEMBL1808264 | D3RKN_42)
Affinity DataKd:  24nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50105753(4-[5-(2-Amino-pyrimidin-4-yl)-4-(4-fluoro-phenyl)-...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50105759(4-{5-(4-Fluoro-phenyl)-3-[1-(2,2,2-trifluoro-ethyl...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM586666(D3RKN_56)
Affinity DataKd:  2.50E+3nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50105752({4-[5-(4-Fluoro-phenyl)-3-(1-methyl-piperidin-4-yl...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM586660(D3RKN_98)
Affinity DataKd:  93nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50215134(CHEMBL104582 | D3RKN_116)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM586664(D3RKN_117)
Affinity DataKd:  92nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM586665(D3RKN_118)
Affinity DataKd:  27nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM586668(D3RKN_119)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM586669(D3RKN_120)
Affinity DataKd:  3.20E+3nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50072400(4-{3-[4-(4-Fluoro-phenyl)-5-(2-methoxy-pyrimidin-4...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50215142(CHEMBL317855 | D3RKN_122)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50215129(CHEMBL106616 | D3RKN_123)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM586676(D3RKN_124)
Affinity DataKd:  200nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50462634(CHEMBL579952 | D3RKN_125)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50368452(CHEMBL4168305)
Affinity DataKd:  370nMAssay Description:Binding affinity to human TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50505542(CHEMBL4576489)
Affinity DataKd:  408nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged TEK (unknown origin) (771 to 1124 residues) expressed in baculovirus infec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50505541(CHEMBL4465866)
Affinity DataKd:  395nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged TEK (unknown origin) (771 to 1124 residues) expressed in baculovirus infec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50588796(CHEMBL5197792)
Affinity DataKd:  950nMAssay Description:Binding affinity to TIE2 (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  240nMAssay Description:Average Binding Constant for TEK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-etho...)
Affinity DataKd:  2.90E+3nMAssay Description:Average Binding Constant for TEK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataKd:  3.00E+3nMAssay Description:Average Binding Constant for TEK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd:  11nMAssay Description:Average Binding Constant for TEK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM21(VANDETANIB | N-(4-bromo-2-fluorophenyl)-6-methoxy-...)
Affinity DataKd:  3.60E+3nMAssay Description:Average Binding Constant for TEK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50097398(CHEMBL449216 | HTS-9026)
Affinity DataKd: >1.00E+4nMAssay Description:Inhibition of TIE2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM239621(US9394309, 147 | US9394309, 74)
Affinity DataKd:  1.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM239621(US9394309, 147 | US9394309, 74)
Affinity DataEC50:  1.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50299148(1-{4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]pyrrolo...)
Affinity DataKd:  350nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50304198(N-(4-(benzo[d]thiazol-2-yl)-3-chlorophenyl)-6-meth...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of TIE2 in human HCT116 cells by cellular phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50304203(2-(4-(6-methoxy-7-(3-(4-methylpiperazin-1-yl)propo...)
Affinity DataEC50:  540nMAssay Description:Inhibition of TIE2 in human HCT116 cells by cellular phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50304193(N-[4-(Benzo[d]thiazol-2''-yl)-2-hydroxyphenyl]-6'-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of TIE2 in human HCT116 cells by cellular phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50304204(2-(4-(6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quin...)
Affinity DataEC50:  140nMAssay Description:Inhibition of TIE2 in human HCT116 cells by cellular phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50304202(N-Methyl-N-[4-(benzo[d]thiazol-2''-yl)-3-methoxyph...)
Affinity DataEC50:  300nMAssay Description:Inhibition of TIE2 in human HCT116 cells by cellular phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Ambit Biosciences

Curated by PubChem BioAssay
LigandPNGBDBM50304194(N-[4-(Benzo[d]thiazol-2''-yl)-2-(trifluoromethoxy)...)
Affinity DataEC50:  2.10E+3nMAssay Description:Inhibition of TIE2 in human HCT116 cells by cellular phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
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