Compile Data Set for Download or QSAR
Report error Found 12 of affinity data for UniProtKB/TrEMBL: Q07890
TargetSon of sevenless homolog 2(Homo sapiens)TBA
LigandPNGBDBM657592(US20240083857, Example 271 | US20240083857, Exampl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged wild-type recombinant human SOS2 catalytic domain (564 to 1043 residues) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)TBA
LigandPNGBDBM657540(US20240083857, Example 219 | N-{1-[5-(6,7-dihydro-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged wild-type recombinant human SOS2 catalytic domain (564 to 1043 residues) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)TBA
LigandPNGBDBM657663(N-{(1R)-1-[3-(1H-imidazol-4-yl)phenyl]ethyl}-6,7-d...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged wild-type recombinant human SOS2 catalytic domain (564 to 1043 residues) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)TBA
LigandPNGBDBM657340(6,7-dimethoxy-N-[(1R)-1-(1-naphthyl)ethyl]quinazol...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged wild-type recombinant human SOS2 catalytic domain (564 to 1043 residues) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)TBA
LigandPNGBDBM50632668(BAY-294)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged wild-type recombinant human SOS2 catalytic domain (564 to 1043 residues) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)TBA
LigandPNGBDBM50614629(BAY-293)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged wild-type recombinant human SOS2 catalytic domain (564 to 1043 residues) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)TBA
LigandPNGBDBM50622917(CHEMBL5413281)
Affinity DataKd:  3.00E+5nMAssay Description:Binding affinity to biotinylated SOS2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)TBA
LigandPNGBDBM23300(7-chloroquinolin-4-amine | CHEMBL44789 | 4-amino-7...)
Affinity DataKd:  3.30E+5nMAssay Description:Binding affinity to biotinylated SOS2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 2(Homo sapiens)TBA
LigandPNGBDBM50622918(CHEMBL5428862)
Affinity DataKd:  4.30E+5nMAssay Description:Binding affinity to biotinylated SOS2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)TBA
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKd:  5.50E+5nMAssay Description:Binding affinity to biotinylated SOS2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 2(Homo sapiens)TBA
LigandPNGBDBM50622920(CHEMBL2321985)
Affinity DataKd:  7.30E+5nMAssay Description:Binding affinity to biotinylated SOS2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 2(Homo sapiens)TBA
LigandPNGBDBM50622919(CHEMBL5418559)
Affinity DataKd:  2.00E+6nMAssay Description:Binding affinity to biotinylated SOS2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed