Compile Data Set for Download or QSAR
Report error Found 23 of affinity data for UniProtKB/TrEMBL: Q07890
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659273BDBM50659273(CHEMBL6159919)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to N-terminal GST tagged SOS2 (562 to 1047 residues) (unknown origin) extracted from Escherichia coli strain BL21 (DE3) assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659274BDBM50659274(CHEMBL6163045)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to N-terminal GST tagged SOS2 (562 to 1047 residues) (unknown origin) extracted from Escherichia coli strain BL21 (DE3) assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659275BDBM50659275(CHEMBL6167330)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to N-terminal GST tagged SOS2 (562 to 1047 residues) (unknown origin) extracted from Escherichia coli strain BL21 (DE3) assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659272BDBM50659272(CHEMBL6164095)
Affinity DataKd:  3.40E+3nMAssay Description:Binding affinity to N-terminal GST tagged SOS2 (562 to 1047 residues) (unknown origin) extracted from Escherichia coli strain BL21 (DE3) assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659270BDBM50659270(CHEMBL1198612)
Affinity DataKd:  4.60E+3nMAssay Description:Binding affinity to N-terminal GST tagged SOS2 (562 to 1047 residues) (unknown origin) extracted from Escherichia coli strain BL21 (DE3) assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659276BDBM50659276(CHEMBL6134434)
Affinity DataKd:  5.30E+3nMAssay Description:Binding affinity to N-terminal GST tagged SOS2 (562 to 1047 residues) (unknown origin) extracted from Escherichia coli strain BL21 (DE3) assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 657592BDBM657592(US20240083857, Example 271 | US20240083857, Exampl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged wild-type recombinant human SOS2 catalytic domain (564 to 1043 residues) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 657540BDBM657540(US20240083857, Example 219 | N-{1-[5-(6,7-dihydro-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged wild-type recombinant human SOS2 catalytic domain (564 to 1043 residues) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 657663BDBM657663(N-{(1R)-1-[3-(1H-imidazol-4-yl)phenyl]ethyl}-6,7-d...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged wild-type recombinant human SOS2 catalytic domain (564 to 1043 residues) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 657340BDBM657340(6,7-dimethoxy-N-[(1R)-1-(1-naphthyl)ethyl]quinazol...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged wild-type recombinant human SOS2 catalytic domain (564 to 1043 residues) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632668BDBM50632668(BAY-294)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged wild-type recombinant human SOS2 catalytic domain (564 to 1043 residues) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614629BDBM50614629(BAY-293)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of N-terminal His10-tagged wild-type recombinant human SOS2 catalytic domain (564 to 1043 residues) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659271BDBM50659271(CHEMBL6146801)
Affinity DataKd:  2.10E+4nMAssay Description:Binding affinity to N-terminal GST tagged SOS2 (562 to 1047 residues) (unknown origin) extracted from Escherichia coli strain BL21 (DE3) assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659278BDBM50659278(CHEMBL6149314)
Affinity DataKd:  2.20E+4nMAssay Description:Binding affinity to N-terminal GST tagged SOS2 (562 to 1047 residues) (unknown origin) extracted from Escherichia coli strain BL21 (DE3) assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659277BDBM50659277(CHEMBL6146220)
Affinity DataKd:  2.40E+4nMAssay Description:Binding affinity to N-terminal GST tagged SOS2 (562 to 1047 residues) (unknown origin) extracted from Escherichia coli strain BL21 (DE3) assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659269BDBM50659269(CHEMBL6168771)
Affinity DataKd:  3.30E+4nMAssay Description:Binding affinity to N-terminal GST tagged SOS2 (562 to 1047 residues) (unknown origin) extracted from Escherichia coli strain BL21 (DE3) assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622917BDBM50622917(CHEMBL5413281)
Affinity DataKd:  3.00E+5nMAssay Description:Binding affinity to biotinylated SOS2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23300BDBM23300(7-chloroquinolin-4-amine | CHEMBL44789 | 4-amino-7...)
Affinity DataKd:  3.30E+5nMAssay Description:Binding affinity to biotinylated SOS2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659279BDBM50659279(CHEMBL6161927)
Affinity DataKd:  3.31E+5nMAssay Description:Binding affinity to N-terminal GST tagged SOS2 (562 to 1047 residues) (unknown origin) extracted from Escherichia coli strain BL21 (DE3) assessed as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622918BDBM50622918(CHEMBL5428862)
Affinity DataKd:  4.30E+5nMAssay Description:Binding affinity to biotinylated SOS2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8961BDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKd:  5.50E+5nMAssay Description:Binding affinity to biotinylated SOS2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622920BDBM50622920(CHEMBL2321985)
Affinity DataKd:  7.30E+5nMAssay Description:Binding affinity to biotinylated SOS2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 2(Homo sapiens)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622919BDBM50622919(CHEMBL5418559)
Affinity DataKd:  2.00E+6nMAssay Description:Binding affinity to biotinylated SOS2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed