TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human SUR1/Kir6.2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATPMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8(Homo sapiens (Human))
University Of Mainz
Curated by ChEMBL
University Of Mainz
Curated by ChEMBL
Affinity DataIC50: 106nMAssay Description:In vitro displacement of [3H]-glibenclamide (IC50=0.61) from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8(Homo sapiens (Human))
University Of Mainz
Curated by ChEMBL
University Of Mainz
Curated by ChEMBL
Affinity DataIC50: 163nMAssay Description:In vitro displacement of [3H]-glibenclamide (IC50=0.61) from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8(Homo sapiens (Human))
University Of Mainz
Curated by ChEMBL
University Of Mainz
Curated by ChEMBL
Affinity DataIC50: 281nMAssay Description:In vitro displacement of [3H]-glibenclamide (IC50=0.61) from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 286nMAssay Description:Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATPMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human SUR1/Kir6.2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.46E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.65E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.87E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.94E+5nMAssay Description:Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATPMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.98E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 2.24E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 3.60E+5nMAssay Description:Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 3.75E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 3.93E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 4.87E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 5.54E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 5.84E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 6.85E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 6.96E+5nMAssay Description:Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 7.40E+5nMAssay Description:Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 7.50E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 8.59E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 8.99E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 9.24E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 9.43E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.35E+6nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataEC50: 530nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataEC50: 3.30E+4nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataEC50: 180nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataEC50: 810nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataEC50: 190nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataEC50: 190nMAssay Description:Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarizationMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataEC50: 3.10E+4nMAssay Description:Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as activation of K+ currentsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataEC50: 356nMAssay Description:Inhibition of Beta-cell KATP channelMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataEC50: 3.20E+4nMAssay Description:Negative log EC50 for Beta-cell KATP channelMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataEC50: 4.00E+3nMAssay Description:Negative log EC50 for Beta-cell KATP channelMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Negative log EC50 for Beta-cell KATP channelMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development
Curated by ChEMBL
Novo Nordisk Research And Development
Curated by ChEMBL
Affinity DataEC50: 530nMAssay Description:Inhibition of Beta-cell KATP channelMore data for this Ligand-Target Pair