Compile Data Set for Download or QSAR
Report error Found 143 of affinity data for UniProtKB/TrEMBL: Q15109
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249571BDBM50249571(CHEMBL4101927 | US10729695, Compound CB-6)
Affinity DataKd:  0.100nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249571BDBM50249571(CHEMBL4101927 | US10729695, Compound CB-6)
Affinity DataKd:  0.300nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 95323BDBM95323(cid_2989573 | SMR000022316 | MLS000044539 | 4-[4-(...)
Affinity DataKd:  0.550nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 802127BDBM802127(US20260109684, RAGE 406R)
Affinity DataKd:  0.600nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 802119BDBM802119(US20260109684, RAGE 283)
Affinity DataKd:  1nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 802122BDBM802122(US20260109684, RAGE 290)
Affinity DataKd:  1nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249574BDBM50249574(CHEMBL4077165 | US10729695, Compound CB-5)
Affinity DataKd:  1nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249574BDBM50249574(CHEMBL4077165 | US10729695, Compound CB-5)
Affinity DataKd:  1nMAssay Description:Binding affinity to RAGE (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249579BDBM50249579(CHEMBL1477694 | US10729695, Compound CB-3)
Affinity DataKd:  1nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249574BDBM50249574(CHEMBL4077165 | US10729695, Compound CB-5)
Affinity DataKd:  1.10nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 32273BDBM32273(MLS000104384 | cid_778626 | SMR000054319 | 2,8-dim...)
Affinity DataKd:  1.20nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 453281BDBM453281(US10729695, Compound CB-14)
Affinity DataKd:  1.40nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249577BDBM50249577(CHEMBL4072531 | US10729695, Compound CB-4)
Affinity DataKd:  2nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 453279BDBM453279(US10729695, Compound CB-8)
Affinity DataKd:  2nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249573BDBM50249573(CHEMBL4063929)
Affinity DataKd:  2nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 802128BDBM802128(US20260109684, RAGE 406S)
Affinity DataKd:  2nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249577BDBM50249577(CHEMBL4072531 | US10729695, Compound CB-4)
Affinity DataKd:  2nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 802129BDBM802129(US20260109684, RAGE 407)
Affinity DataKd:  2nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249575BDBM50249575(CHEMBL4100986 | US10729695, Compound CB-10)
Affinity DataKd:  3nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 802121BDBM802121(US20260109684, RAGE 289)
Affinity DataKd:  3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 802126BDBM802126(US20260109684, RAGE 406)
Affinity DataKd:  3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 802125BDBM802125(US20260109684, RAGE 402)
Affinity DataKd:  3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249575BDBM50249575(CHEMBL4100986 | US10729695, Compound CB-10)
Affinity DataKd:  3.10nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249576BDBM50249576(CHEMBL4075539 | US10729695, Compound CD-6)
Affinity DataKd:  4nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249576BDBM50249576(CHEMBL4075539 | US10729695, Compound CD-6)
Affinity DataKd:  4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249572BDBM50249572(CHEMBL1463447 | US10729695, Compound CB-1)
Affinity DataKd:  4nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249572BDBM50249572(CHEMBL1463447 | US10729695, Compound CB-1)
Affinity DataKd:  6nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 453285BDBM453285(US10729695, Compound CB-2)
Affinity DataKd:  6.5nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 802124BDBM802124(US20260109684, RAGE 299)
Affinity DataKd:  8nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 582522BDBM582522(US11524942, Compound M5)
Affinity DataKd:  9.70nMAssay Description:The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 582526BDBM582526(US11524942, Compound M6)
Affinity DataKd:  9.80nMAssay Description:The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 802123BDBM802123(US20260109684, RAGE 291)
Affinity DataKd:  12nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249580BDBM50249580(Azeliragon | PF-04494700 | TTP448 | US11524942, Co...)
Affinity DataKd:  12.7nMAssay Description:The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249580BDBM50249580(Azeliragon | PF-04494700 | TTP448 | US11524942, Co...)
Affinity DataKd:  13nMAssay Description:Binding affinity to recombinant human RAGE assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249570BDBM50249570(CHEMBL4066660)
Affinity DataKd:  15nMAssay Description:Binding affinity to RAGE (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249570BDBM50249570(CHEMBL4066660)
Affinity DataKd:  15nMAssay Description:Binding affinity to human RAGE domain V by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249579BDBM50249579(CHEMBL1477694 | US10729695, Compound CB-3)
Affinity DataKd:  18nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 802120BDBM802120(US20260109684, RAGE 286)
Affinity DataKd:  20nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 582520BDBM582520(US11524942, Compound M2)
Affinity DataKd:  22.3nMAssay Description:The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249567BDBM50249567(CHEMBL4075936)
Affinity DataKi:  25nMAssay Description:Inhibition of amyloid beta binding to RAGE (unknown origin) transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249567BDBM50249567(CHEMBL4075936)
Affinity DataKi:  25nMAssay Description:Displacement of [I125]amyloid beta (1 to 40) from human RAGE domain V expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249566BDBM50249566(CHEMBL4085254)
Affinity DataKd:  30nMAssay Description:Binding affinity to human C-terminal His-tagged RAGE domain V (24 to 125 residues) expressed in Escherichia coli BL21(DE3) by tryptophan fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249582BDBM50249582(CHEMBL1547178 | US10729695, Compound CB-13)
Affinity DataKd:  32nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 26115BDBM26115(pyridine-2,3-dicarboxylic acid | CHEMBL286204 | Qu...)
Affinity DataKd:  43nMAssay Description:Binding affinity to human His-tagged RAGE domain VC1 expressed in Escherichia coli by fluorescence titration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 453292BDBM453292(US10729695, Compound CD-4)
Affinity DataKd:  75nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 453304BDBM453304(US10729695, Compound CD-29)
Affinity DataKd:  78nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 582527BDBM582527(US11524942, Compound M7)
Affinity DataKd:  99.8nMAssay Description:The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249582BDBM50249582(CHEMBL1547178 | US10729695, Compound CB-13)
Affinity DataKd:  123nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 50249567BDBM50249567(CHEMBL4075936)
Affinity DataKi:  148nMAssay Description:Inhibition of HMGB1 binding to human RAGE domain V expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
The State University of New York

US Patent
LigandChemical structure of BindingDB Monomer ID 582518BDBM582518(US11524942, Compound M1)
Affinity DataKd:  219nMAssay Description:The binding affinity of COMPOUND I and compounds of the invention to human sRAGE (the soluble extracellular domain of the human receptor for advanced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
US Patent

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