Compile Data Set for Download or QSAR
maximum 50k data
Found 47 of affinity data for UniProtKB/TrEMBL: Q28175
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580509(CHEMBL5083918)
Affinity DataIC50:  50nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580504(CHEMBL5091011)
Affinity DataIC50:  95nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323432(3-Amino-1-(3-((4,4-Difluorocyclohexyl)Methoxy)Phen...)
Affinity DataIC50:  103nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580510(CHEMBL5094849)
Affinity DataIC50:  124nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580501(CHEMBL5069771)
Affinity DataIC50:  132nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580501(CHEMBL5069771)
Affinity DataIC50:  132nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580499(CHEMBL5081450)
Affinity DataIC50:  145nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580511(CHEMBL5081640)
Affinity DataIC50:  169nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323415(3-Amino-1-(3-(cyclohexylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataIC50:  172nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580508(CHEMBL5094949)
Affinity DataIC50:  177nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580500(CHEMBL5077356)
Affinity DataIC50:  184nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580500(CHEMBL5077356)
Affinity DataIC50:  184nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323415(3-Amino-1-(3-(cyclohexylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataIC50:  190nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580503(CHEMBL5084662)
Affinity DataIC50:  201nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323432(3-Amino-1-(3-((4,4-Difluorocyclohexyl)Methoxy)Phen...)
Affinity DataIC50:  269nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580505(CHEMBL5083435)
Affinity DataIC50:  274nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580506(CHEMBL5092414)
Affinity DataIC50:  284nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580505(CHEMBL5083435)
Affinity DataIC50:  287nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580502(CHEMBL5086566)
Affinity DataIC50:  292nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50546390(CHEMBL4757869)
Affinity DataIC50:  323nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50580507(CHEMBL5076106)
Affinity DataIC50:  358nMAssay Description:Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323450((S)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323419((R)-3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323448(4-((3-(3-Amino-1-Hydroxypropyl)Phenoxy)Methyl)Hept...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323418(3-Amino-1-(3-(2-Propylpentyloxy)Phenyl)Propan-1-Ol...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323447(3-Amino-1-(3-(Cycloheptylmethoxy)Phenyl)Propan-1-O...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323417(3-Amino-1-(3-(Cycloheptylmethoxy)Phenyl)Propan-1-O...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323500(3-(3-(Cycloheptylmethoxy)Phenyl)Propan-1-Amine | U...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323416(1-((3-(3-Amino-1-Hydroxypropyl)Phenoxy)Methyl)Cycl...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323446(1-((3-(3-Amino-1-Hydroxypropyl)Phenoxy)Methyl)Cycl...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323499(1-((3-(3-Aminopropyl)Phenoxy)Methyl)Cycloheptanol ...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323445(1-((3-(3-Aminopropyl)Phenoxy)Methyl)Cyclohexanol |...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323444(2-(3-(Cycloheptylmethoxy)Phenoxy)Ethanamine | US10...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323442(2-(3-(Cyclohexylmethoxy)Phenoxy)Ethanamine | US101...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323441(1-Amino-3-(3-(Cyclohexylmethoxy)Phenyl)Propan-2-Ol...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323440(3-Amino-1-(3-(Cyclohexylmethoxy)Phenyl)Propan-1-On...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323415(3-Amino-1-(3-(cyclohexylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323439(3-(3-(2-Ethylbutoxy)Phenyl)Propan-I-Amine | US1018...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323437(3-(3-(Cyclohexylmethoxy)Phenyl)Propan-1-Amine | US...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323438(3-(3-(2-Propylpentyloxy)Phenyl)Propan-1-Amine | US...)
Affinity DataIC50: <1.00E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323586(N-(3-(3-(Cyclohexylmethoxy)Phenyl)-3-Hydroxypropyl...)
Affinity DataIC50:  5.50E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323501(1-((3-(2-Aminoethoxy)Phenoxy)Methyl)Cycloheptanol ...)
Affinity DataIC50:  5.50E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323498(2-(3-(Benzyloxy)Phenoxy)Ethanamine | US10188615, E...)
Affinity DataIC50:  5.50E+3nMAssay Description:Isomerase inhibition reactions were performed essentially as described (Stecher et al., J. Biol. Chem. 274:8577-85 (1999); see also Golczak et al., P...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50546391(CHEMBL4795212)
Affinity DataEC50:  197nMAssay Description:Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production using all-trans-retinol as substrate pre-incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50546390(CHEMBL4757869)
Affinity DataEC50:  323nMAssay Description:Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production using all-trans-retinol as substrate pre-incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM323415(3-Amino-1-(3-(cyclohexylmethoxy)Phenyl)Propan-1-Ol...)
Affinity DataEC50:  172nMAssay Description:Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production using all-trans-retinol as substrate pre-incubated wi...More data for this Ligand-Target Pair
TargetRetinoid isomerohydrolase(Bos taurus (Bovine))
Bar-Ilan University

Curated by ChEMBL
LigandPNGBDBM50546391(CHEMBL4795212)
Affinity DataEC50:  196nMAssay Description:Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production using all-trans-retinol as substrate pre-incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed