Compile Data Set for Download or QSAR
maximum 50k data
Found 25 of affinity data for UniProtKB/TrEMBL: Q61143
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM21164(1-[2-(4-methoxyphenyl)-2-[3-(4-methoxyphenyl)propo...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of mouse TRPC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM77617(4-methyl-2-(1-piperidinyl)quinoline | 4-methyl-2-p...)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of HA-tagged mouse TRPC6 expressed in HEK293 cells assessed as reduction in acetylcholine-induced membrane potential by FLIPR membrane pot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50465054(CHEMBL4281262)
Affinity DataIC50:  2.45E+4nMAssay Description:Inhibition of mouse TRPC6 expressed in HEK293 cells assessed as reduction in M085-induced intracellular calcium flux pretreated for 5 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50465053(CHEMBL4293440)
Affinity DataIC50:  2.56E+4nMAssay Description:Inhibition of mouse TRPC6 expressed in HEK293 cells assessed as reduction in M085-induced intracellular calcium flux pretreated for 5 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50519474(CHEMBL4436705)
Affinity DataIC50:  5.71E+4nMAssay Description:Inhibition of mouse TRPC6 expressed in HEK293 cells co-expressing M5 receptor assessed as reduction in carbachol-induced membrane potential by FMP-2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50492279(CHEMBL1376358)
Affinity DataIC50:  5.96E+4nMAssay Description:Inhibition of mouse TRPC6 expressed in HEK293 cells co-expressing M5 receptor assessed as reduction in carbachol-induced membrane potential by FMP-2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50519475(CHEMBL4438838)
Affinity DataIC50:  6.38E+4nMAssay Description:Inhibition of mouse TRPC6 expressed in HEK293 cells co-expressing M5 receptor assessed as reduction in carbachol-induced membrane potential by FMP-2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50492280(CHEMBL2396911)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse TRPC6 expressed in HEK293 cells co-expressing M5 receptor assessed as reduction in carbachol-induced membrane potential by FMP-2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50492274(CHEMBL2396912)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse TRPC6 expressed in HEK293 cells co-expressing M5 receptor assessed as reduction in carbachol-induced membrane potential by FMP-2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50492273(CHEMBL2396913)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse TRPC6 expressed in HEK293 cells co-expressing M5 receptor assessed as reduction in carbachol-induced membrane potential by FMP-2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50519468(CHEMBL4440241)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse TRPC6 expressed in HEK293 cells co-expressing M5 receptor assessed as reduction in carbachol-induced membrane potential by FMP-2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239167(CHEMBL1496110)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as induction of membrane potential de...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239161(CHEMBL4085233)
Affinity DataEC50:  1.39E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239167(CHEMBL1496110)
Affinity DataEC50:  4.66E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239162(CHEMBL4060400)
Affinity DataEC50:  3.91E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239167(CHEMBL1496110)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as peak current changes at +80 mV by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239167(CHEMBL1496110)
Affinity DataEC50:  7.20E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239166(CHEMBL4083411)
Affinity DataEC50:  1.23E+4nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239165(CHEMBL4079835)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239164(CHEMBL4080748)
Affinity DataEC50:  2.88E+4nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239160(CHEMBL4060387)
Affinity DataEC50:  7.79E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239163(CHEMBL4069075)
Affinity DataEC50:  8.00E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239162(CHEMBL4060400)
Affinity DataEC50:  3.24E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as peak current changes at +80 mV by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239160(CHEMBL4060387)
Affinity DataEC50:  2.05E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as peak current changes at +80 mV by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50239161(CHEMBL4085233)
Affinity DataEC50:  890nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as peak current changes at +80 mV by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed