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Report error Found 3097 of affinity data for UniProtKB/TrEMBL: Q86WV6
TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604469BDBM50604469(CHEMBL5187131)
Affinity DataEC50:  0.00400nMAssay Description:Agonist activity at STING in human wild-type THP1-Dual cells co-expressing ISRE reporter assessed as IRF-mediated immune response incubated for 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 730218BDBM730218(US20250108123, Example II-1)
Affinity DataIC50: 0.0600nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 665297BDBM665297(US20240116909, Example 1 | 4-(5-(3-((2-(3-carboxyp...)
Affinity DataIC50: 0.0600nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604466BDBM50604466(CHEMBL5201766)
Affinity DataIC50: 0.0623nMAssay Description:Binding affinity to recombinant human His-tagged STING by measuring fluorescent signals in the presence of d2 labelled STING wild type ligand by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 730205BDBM730205(4,4'-((propane-1,3-diylbis(oxy))bis(6-methoxyisoin...)
Affinity DataIC50: 0.100nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50509050BDBM50509050(CHEMBL4438309)
Affinity DataEC50: <0.100nMAssay Description:Binding affinity to 6His-tagged human STING measured after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50509050BDBM50509050(CHEMBL4438309)
Affinity DataEC50: <0.100nMAssay Description:Activation of human STING (139 to 379 residues) expressed in THP1-Blue ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 730221BDBM730221(US20250108123, Example II-4)
Affinity DataIC50: 0.180nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 665300BDBM665300(US20240116909, Example 4 | 4-(5-(3-((2-(3-carboxyp...)
Affinity DataIC50: 0.180nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 730235BDBM730235(US20250108123, Example II-20)
Affinity DataIC50: 0.190nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 665315BDBM665315(US20240116909, Example 20 | 4-(5-(3-((2-(3-carboxy...)
Affinity DataIC50: 0.190nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 490791BDBM490791(US10968242, Example 18 | 9-((4S,6R,7S,11aR,13R,14R...)
Affinity DataKi:  0.190nMAssay Description:A radioligand binding assay was developed to determine compound interactions were competitive with a tritium-labeled version of the native STING liga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 730232BDBM730232(US20250108123, Example II-17)
Affinity DataIC50: 0.190nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 665312BDBM665312(US20240116909, Example 17 | (S)-4-(5-(3-((2-((S)-3...)
Affinity DataIC50: 0.190nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 577477BDBM577477(US11472830, Cpd No. 9)
Affinity DataKd:  0.195nMAssay Description:Compounds were analyzed on an 5200 biacore SPR instrument (GE Healthcare). E.coli produced truncated STING protein was immobilized on a series S stre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587689BDBM50587689(CHEMBL5197229)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to human STING (137 to 379 residues) assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 490777BDBM490777(US10968242, Example 3 Peak 4)
Affinity DataKi:  0.200nMAssay Description:A radioligand binding assay was developed to determine compound interactions were competitive with a tritium-labeled version of the native STING liga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 490773BDBM490773(US10968242, Example 2 Peak 4)
Affinity DataKi:  0.200nMAssay Description:A radioligand binding assay was developed to determine compound interactions were competitive with a tritium-labeled version of the native STING liga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604556BDBM50604556(CHEMBL5175703)
Affinity DataIC50: 0.200nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 490791BDBM490791(US10968242, Example 18 | 9-((4S,6R,7S,11aR,13R,14R...)
Affinity DataKd:  0.200nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 665306BDBM665306(US20240116909, Example 10 | 4-(5-(3-((2-(3-carboxy...)
Affinity DataIC50: 0.280nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 665306BDBM665306(US20240116909, Example 10 | 4-(5-(3-((2-(3-carboxy...)
Affinity DataIC50: 0.280nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 490790BDBM490790(US10968242, Example 17 Peak 2)
Affinity DataKd:  0.300nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 490790BDBM490790(US10968242, Example 17 Peak 2)
Affinity DataKi:  0.300nMAssay Description:A radioligand binding assay was developed to determine compound interactions were competitive with a tritium-labeled version of the native STING liga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [155-341,H232R](Homo sapiens (Human))
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 669432BDBM669432(US11964978, Example AIF11)
Affinity DataKi:  0.300nMAssay Description:A radioligand binding assay was developed to determine whether compound interactions were competitive with a tritium-labeled version of the native ST...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 490777BDBM490777(US10968242, Example 3 Peak 4)
Affinity DataKd:  0.300nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50509399BDBM50509399(CHEMBL4468010)
Affinity DataIC50: 0.300nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 665301BDBM665301(US20240116909, Example 5 | Sodium (S)-4-(5-(3-((2-...)
Affinity DataIC50: 0.320nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 730212BDBM730212(US20250108123, Example I-9)
Affinity DataIC50: 0.320nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 730222BDBM730222(sodium (S)-4-(5-(3-((2-((S)-3-carboxylatobutanoyl)...)
Affinity DataIC50: 0.320nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604466BDBM50604466(CHEMBL5201766)
Affinity DataEC50:  0.354nMAssay Description:Agonist activity at STING in human wild-type THP1-Dual cells co-expressing ISRE reporter assessed as IRF-mediated immune response incubated for 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 665302BDBM665302(US20240116909, Example 6 | Sodium (S)-4-(5-(3-((2-...)
Affinity DataIC50: 0.360nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 730223BDBM730223(US20250108123, Example II-7)
Affinity DataIC50: 0.360nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 457787BDBM457787(US10738074, Example 18)
Affinity DataEC50:  0.400nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 490772BDBM490772(US10968242, Example 2 Peak 3)
Affinity DataKd:  0.440nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 490790BDBM490790(US10968242, Example 17 Peak 2)
Affinity DataKd:  0.5nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 730225BDBM730225(US20250108123, Example II-9)
Affinity DataIC50: 0.650nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 665304BDBM665304(US20240116909, Example 8 | Sodium 4-(5-(3-((2-(3-c...)
Affinity DataIC50: 0.650nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 730208BDBM730208(US20250108123, Example I-4)
Affinity DataIC50: 0.680nMAssay Description:Cisbio Bioassays' human STING WT binding assay (#64BDSTGPEG & 64BDSTGPEH, Cisbio) is for quantitative measurement of human STING WT ligand using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50509421BDBM50509421(CHEMBL4577528)
Affinity DataIC50: 0.700nMAssay Description:Displacement of radiolabeled [3H]-2',3'-cGAMP from wild type human STING incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 490773BDBM490773(US10968242, Example 2 Peak 4)
Affinity DataKd:  0.780nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632884BDBM50632884(CHEMBL5435411)
Affinity DataKd:  0.789nMAssay Description:Binding affinity to His-tagged wild type human STING C-terminal domain (149 to 379 residues) expressed in Escherichia coli BL21 (DE3) cells assessed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 457789BDBM457789(US10738074, Example 19)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 457790BDBM457790(US10738074, Example 20)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547942BDBM50547942(CHEMBL4764478)
Affinity DataEC50:  1nMAssay Description:Agonist activity at STING in human PBMC cells assessed as increase in IFNp by electrochemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 573876BDBM573876(US11453697, Example 71 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547941BDBM50547941(CHEMBL4755632)
Affinity DataEC50: <1nMAssay Description:Agonist activity at STING in human PBMC cells assessed as increase in IFNp by electrochemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 457787BDBM457787(US10738074, Example 18)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547940BDBM50547940(CHEMBL4800391)
Affinity DataEC50: <1nMAssay Description:Agonist activity at STING in human PBMC cells assessed as increase in IFNp by electrochemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 573874BDBM573874(US11453697, Example 69 | 5-amino-3- [(5R,7R,8R,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

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