Compile Data Set for Download or QSAR
Report error Found 491 of affinity data for UniProtKB/TrEMBL: Q8IVH8
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.0830nMAssay Description:Inhibition of human GLK using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 0.0830nMAssay Description:Inhibition of human GLK using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50552697(CHEMBL4780798)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of GLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50634668(CHEMBL5505932)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of GLK (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50618965(CHEMBL5428695)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of GLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human GLK/MAP4K3 using myelin basic protein as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50552696(CHEMBL4778959)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704507(3-(3-Chloro-4-morpholino-anilino)-5-(methylamino)-...)
Affinity DataIC50: 3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50548192(CHEMBL4749141 | US20240300941, Compound A7)
Affinity DataIC50: 3nMAssay Description:Inhibition of GLK (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50618955(CHEMBL5396693)
Affinity DataIC50: 3nMAssay Description:Inhibition of GLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704632(5-Cyclopropyl-3-[(1-methyl-2,2-dioxo-3H-2,1-benzot...)
Affinity DataIC50: 3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704562(3-[3-Cyano-4-[(3S,5R)-3,5-dimethylpiperazin-1-yl]a...)
Affinity DataIC50: 3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704598(5-Cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-y...)
Affinity DataIC50: 3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704614(5-Cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-y...)
Affinity DataIC50: 3nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704554(5-(Methylamino)-3-[4-(8-methyl-3,8-diazabicyclo[3....)
Affinity DataIC50: 4nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704581(5-(Methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7...)
Affinity DataIC50: 4nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704488(5-Cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-y...)
Affinity DataIC50: 4nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704556(3-[4-[(3S,5R)-3,5-Dimethylpiperazin-1-yl]-3,5-difl...)
Affinity DataIC50: 4nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704599(5-Cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-y...)
Affinity DataIC50: 4nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704615(3-[3,5-Difluoro-4-[(1-methyl-4-piperidyl)oxy]anili...)
Affinity DataIC50: 4nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704631(5-(Methylamino)-3-[(1-methyl-2,2-dioxo-3H-2,1-benz...)
Affinity DataIC50: 4nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704646(5-(Methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7...)
Affinity DataIC50: 4nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704576(5-(Methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7...)
Affinity DataIC50: 5nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704533(5-Cyclopropyl-3-[4-(1-hydroxy-1-methyl-ethyl)anili...)
Affinity DataIC50: 5nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50548194(CHEMBL4762312)
Affinity DataIC50: 5nMAssay Description:Inhibition of GLK (unknown origin) by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704559(3-[4-[(3S,5R)-3,5-Dimethylpiperazin-1-yl]-3,5-dime...)
Affinity DataIC50: 5nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704616(3-[4-[(1-Isopropyl-4-piperidyl)oxy]anilino]-5-(met...)
Affinity DataIC50: 5nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704563(3-[2,3-Difluoro-4-[4-(4-methylpiperazin-1-yl)-1-pi...)
Affinity DataIC50: 5nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704610(3-[4-[(1-Acetyl-4-piperidyl)oxy]anilino]-5-(methyl...)
Affinity DataIC50: 5nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704577(5-(Methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7...)
Affinity DataIC50: 5nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  5.10nMAssay Description:Binding constant for MAP4K3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataKd:  5.10nMAssay Description:Inhibition of GLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704580(5-(Methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7...)
Affinity DataIC50: 6nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704579(5-(Methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7...)
Affinity DataIC50: 6nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704611(5-(Methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7...)
Affinity DataIC50: 6nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704578(5-(Methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7...)
Affinity DataIC50: 6nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704639(3-[4-(1,1-Dioxothiazinan-2-yl)anilino]-5-(methylam...)
Affinity DataIC50: 7nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50632515(CHEMBL5397290)
Affinity DataIC50: 7nMAssay Description:Inhibition of MAP4K3 (unknown origin) by by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704652(5-(Methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7...)
Affinity DataIC50: 7nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704609(5-(Methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7...)
Affinity DataIC50: 7nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50635995(CHEMBL5558185)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of GLK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50161957(CHEMBL180022 | N-(4-(3-chloro-4-(pyridin-2-ylmetho...)
Affinity DataKd:  7.70nMAssay Description:Binding constant for MAP4K3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704634(3-[4-(1,1-Dioxo-1,4-thiazinan-4-yl)anilino]-5-(met...)
Affinity DataIC50: 8nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704645(3-[4-(tert-Butylsulfonimidoyl)anilino]-5-(methylam...)
Affinity DataIC50: 8nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704564(3-[[6-(4-Isopropylpiperazin-1-yl)-5-methyl-3-pyrid...)
Affinity DataIC50: 8nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704510(3-(3-Cyano-4-morpholino-anilino)-5-(methylamino)-6...)
Affinity DataIC50: 8nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704589(3-[3-Chloro-4-[(4-methylpiperazin-1-yl)methyl]anil...)
Affinity DataIC50: 8nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM704508(5-(Methylamino)-6-(3-methylimidazo[4,5-c]pyridin-7...)
Affinity DataIC50: 8nMAssay Description:The luminescent signal generated is proportional to the ADP concentration produced in a kinase assay in the presence and absence of the compound(s) a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  8.20nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2011
Entry Details
PCBioAssay
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  8.20nMAssay Description:Binding constant for MAP4K3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
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