Affinity DataIC50: 1nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of URAT1 (unknown origin) assessed as decrease in uric acid level measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 6nMAssay Description:Inhibition of URAT1 (unknown origin) assessed as decrease in uric acid level measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 7nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation cou...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The resultin...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The resultin...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The resultin...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:a. Construction of a Cell Line Stably Expressing hURAT1hURAT1 plasmid was transfected into HEK293T cell, and a cell line stably expressing hURAT1 was...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The resultin...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The resultin...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:a. Construction of a Cell Line Stably Expressing hURAT1hURAT1 plasmid was transfected into HEK293T cell, and a cell line stably expressing hURAT1 was...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The resultin...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The resultin...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The resultin...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The resultin...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:In vitro URAT1 assay can be used to identify compounds having potential activity for decreasing serum uric acid. In a suitable test, the vectors that...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:a. Construction of a Cell Line Stably Expressing hURAT1hURAT1 plasmid was transfected into HEK293T cell, and a cell line stably expressing hURAT1 was...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 21nMAssay Description:URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 21.5nMAssay Description:URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The resultin...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The resultin...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The resultin...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Human embryonic kidney cells (HEK293) was incubated in DMEM tissue culture medium, at 37° C., under 5% CO2 and 95% air atmosphere. TransIT-293 transf...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:It was introduced human URAT1 full-length cDNA into an expression vector pcDNA5 / FRT / V5-His TOPO (registered trademark) (Invitrogen). The resultin...More data for this Ligand-Target Pair
