Compile Data Set for Download or QSAR
Report error Found 67 of affinity data for UniProtKB/TrEMBL: Q99714
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  51nMAssay Description:Binding affinity to human HSD17B10 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634404(CHEMBL5441071)
Affinity DataIC50: 95nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using ALLOP as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634402(CHEMBL5423014)
Affinity DataKi:  230nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as residual activity using acetoacetyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634403(CHEMBL5433004)
Affinity DataKi:  250nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as residual activity using acetoacetyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634407(CHEMBL5433229)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using ALLOP as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM232926(US9346839, 7 | US9738668, Compound 7)
Affinity DataKi:  2.80E+3nM ΔG°:  -31.7kJ/mole IC50: 9.90E+3nM Kd:  256nMpH: 7.3 T: 2°CAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details
US Patent

Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM232931(US9346839, 15 | US9738668, Compound 15)
Affinity DataKi:  3.56E+5nM ΔG°:  -19.7kJ/mole IC50: 1.26E+6nM Kd:  264nMpH: 7.4 T: 2°CAssay Description:The interactions between compounds and ABAD were performed using the dual flow cell BIACORE 3000 instrument. Surface Plasmon Resonance (SPR) studies ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details
US Patent

Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM232928(US9346839, 9 | US9738668, Compound 9)
Affinity DataKi:  2.00E+3nM ΔG°:  -32.5kJ/mole IC50: 7.20E+3nM Kd:  264nMpH: 7.3 T: 2°CAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details
US Patent

Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634405(CHEMBL5419196)
Affinity DataIC50: 270nMAssay Description:Mixed type inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634406(CHEMBL5403203)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using ALLOP as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)
Affinity DataKi:  1.49E+4nM ΔG°:  -27.5kJ/mole IC50: 5.27E+4nM Kd:  291nMpH: 7.4 T: 2°CAssay Description:The interactions between compounds and ABAD were performed using the dual flow cell BIACORE 3000 instrument. Surface Plasmon Resonance (SPR) studies ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details
US Patent

Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634402(CHEMBL5423014)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as residual activity using acetoacetyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634405(CHEMBL5419196)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using ALLOP as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634407(CHEMBL5433229)
Affinity DataIC50: 340nMAssay Description:Mixed type inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634403(CHEMBL5433004)
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as residual activity using acetoacetyl-CoA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM232930(US9346839, 11 | US9738668, Compound 11)
Affinity DataKi:  9.60E+3nM ΔG°:  -28.6kJ/mole IC50: 3.41E+4nM Kd:  380nMpH: 7.3 T: 2°CAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details
US Patent

Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634404(CHEMBL5441071)
Affinity DataIC50: 410nMAssay Description:Mixed type inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50650320(CHEMBL5629856)
Affinity DataKi:  440nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as residual activity using acetoacetyl-CoA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)
Affinity DataKi:  9.66E+4nM ΔG°:  -22.9kJ/mole IC50: 3.41E+5nM Kd:  496nMpH: 7.4 T: 2°CAssay Description:The interactions between compounds and ABAD were performed using the dual flow cell BIACORE 3000 instrument. Surface Plasmon Resonance (SPR) studies ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details
US Patent

Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)
Affinity DataKi:  5.50E+3nM ΔG°:  -30.0kJ/mole IC50: 1.96E+4nM Kd:  496nMpH: 7.3 T: 2°CAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details
US Patent

Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634406(CHEMBL5403203)
Affinity DataIC50: 520nMAssay Description:Mixed type inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50650320(CHEMBL5629856)
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as residual activity using acetoacetyl-CoA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50650321(CHEMBL5625122)
Affinity DataKi:  650nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as residual activity using acetoacetyl-CoA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634393(CHEMBL5405943)
Affinity DataIC50: 780nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50650321(CHEMBL5625122)
Affinity DataIC50: 840nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as residual activity using acetoacetyl-CoA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50650317(CHEMBL5624878)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant 17beta-HSD10 expressed in bacterial expression system assessed as decrease in NADH using acetoacetyl-CoA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634400(CHEMBL5431963)
Affinity DataIC50: 930nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM232924(US9346839, 5 | US9738668, Compound 5)
Affinity DataKi:  9.11E+4nM ΔG°:  -23.1kJ/mole IC50: 3.35E+5nM Kd:  954nMpH: 7.3 T: 2°CAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2017
Entry Details
US Patent

Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634397(CHEMBL5433091)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634403(CHEMBL5433004)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50650318(CHEMBL5624707)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant 17beta-HSD10 expressed in bacterial expression system assessed as decrease in NADH using acetoacetyl-CoA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50650315(CHEMBL5624823)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant 17beta-HSD10 expressed in bacterial expression system assessed as decrease in NADH using acetoacetyl-CoA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634395(CHEMBL5430387)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634401(CHEMBL5417931)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50650316(CHEMBL5630797)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant 17beta-HSD10 expressed in bacterial expression system assessed as decrease in NADH using acetoacetyl-CoA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50650319(CHEMBL5631193)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant 17beta-HSD10 expressed in bacterial expression system assessed as decrease in NADH using acetoacetyl-CoA as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634399(CHEMBL5401015)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634402(CHEMBL5423014)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634394(CHEMBL5410530)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of HSD17B10 (unknown origin) incubated for 1 hr by colloidal coomassie staining based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634398(CHEMBL5417691)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634399(CHEMBL5401015)
Affinity DataIC50: 4.39E+3nMAssay Description:Inhibition of 17beta-HSD10 (unknown origin) expressed in HEK293 cells using (-)-CHANA probe as substrate assessed as decrease in fluorescence intensi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634400(CHEMBL5431963)
Affinity DataIC50: 4.76E+3nMAssay Description:Inhibition of 17beta-HSD10 (unknown origin) expressed in HEK293 cells using (-)-CHANA probe as substrate assessed as decrease in fluorescence intensi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634398(CHEMBL5417691)
Affinity DataIC50: 5.45E+3nMAssay Description:Inhibition of 17beta-HSD10 (unknown origin) expressed in HEK293 cells using (-)-CHANA probe as substrate assessed as decrease in fluorescence intensi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634406(CHEMBL5403203)
Affinity DataIC50: 6.21E+3nMAssay Description:Inhibition of 17beta-HSD10 (unknown origin) expressed in HEK293 cells using (-)-CHANA probe as substrate assessed as decrease in fluorescence intensi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634396(CHEMBL5426952)
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of recombinant 17beta-HSD10 (unknown origin) using E2 as substrate and NAD+ as cofactor preincubated for 5 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634401(CHEMBL5417931)
Affinity DataIC50: 9.03E+3nMAssay Description:Inhibition of 17beta-HSD10 (unknown origin) expressed in HEK293 cells using (-)-CHANA probe as substrate assessed as decrease in fluorescence intensi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50634393(CHEMBL5405943)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of 17beta-HSD10 (unknown origin) expressed in HEK293 cells using (-)-CHANA probe as substrate assessed as decrease in fluorescence intensi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50652792(CHEMBL3752910)
Affinity DataKd:  2.65E+4nMAssay Description:Binding affinity to human HSD17B10 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target3-hydroxyacyl-CoA dehydrogenase type-2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM667328(US11957687, Compound 50 | N-(3,6-dichloro-9H-xanth...)
Affinity DataIC50: 3.00E+4nMAssay Description:To screen compounds of the disclosure for their ability to block HSD17B10 function, an enzymatic blocking assay was performed. For the assay, HSD17B1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
US Patent

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