Compile Data Set for Download or QSAR
maximum 50k data
Found 130 of affinity data for UniProtKB/TrEMBL: Q9BVS4
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50572240(CHEMBL4857685)
Affinity DataIC50:  130nMAssay Description:Inhibition of RIOK2 in human VCaP cells after 48 hrs by Western blotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50605906(CHEMBL5172767)
Affinity DataIC50:  139nMAssay Description:Inhibition of N-terminal hexahistidine-SUMO-tagged human full length RIOK2 (residues 1 to 321) expressed in Escherichia coli BL21 (DE3) incubated for...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550131(CHEMBL4754904)
Affinity DataIC50:  5.00E+3nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550129(CHEMBL4744511)
Affinity DataIC50:  5.20E+3nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550132(CHEMBL4749658)
Affinity DataIC50:  5.20E+3nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550137(CHEMBL4750817)
Affinity DataIC50:  5.30E+3nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50401152(CHEMBL2205766)
Affinity DataIC50: <5.89E+3nMAssay Description:Inhibition of RIOK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550133(CHEMBL4754518)
Affinity DataIC50:  6.60E+3nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550133(CHEMBL4754518)
Affinity DataIC50:  6.60E+3nMAssay Description:Displacement of fluorescent tracer K5 from N-terminal full-length NanoLuc-fused RIOK2 (unknown origin) expressed in HEK293 cells using NanoGlo substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550128(CHEMBL4777902)
Affinity DataIC50:  7.50E+3nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550142(CHEMBL4799148)
Affinity DataIC50:  7.60E+3nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550134(CHEMBL4748932)
Affinity DataIC50:  7.60E+3nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550130(CHEMBL4785960)
Affinity DataIC50:  1.34E+4nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550138(CHEMBL4749115)
Affinity DataIC50:  1.45E+4nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550127(CHEMBL4781866)
Affinity DataIC50:  1.46E+4nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550127(CHEMBL4781866)
Affinity DataIC50:  1.46E+4nMAssay Description:Displacement of fluorescent tracer K5 from N-terminal full-length NanoLuc-fused RIOK2 (unknown origin) expressed in HEK293 cells using NanoGlo substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550139(CHEMBL4786052)
Affinity DataIC50:  2.80E+4nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550136(CHEMBL4765173)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550135(CHEMBL4794407)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550141(CHEMBL4791951)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50550140(CHEMBL4745254)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd:  6.70E+3nMAssay Description:Binding affinity to RIOK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)
Affinity DataKd:  97nMAssay Description:Binding affinity to RIOK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)
Affinity DataKd:  6.70E+3nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)
Affinity DataKd:  97nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataKd:  390nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to RIOK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)
Affinity DataKd:  49nMAssay Description:Binding affinity to RIOK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM13535(4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to RIOK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to RIOK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50326054(CHEMBL1240703)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to RIOK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  140nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM17055((18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-tr...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM60589(6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM31088(1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-y...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)
Affinity DataKd:  2.60E+3nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataKd:  770nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM12621(2,4-Diamino-5-ketopyrimidine 39 | 5-[(2,3-difluoro...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM25117(AG-013736 | AXITINIB | N-methyl-2-({3-[(E)-2-(pyri...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM6568(6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylsulfa...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM25919(BMS-345541 | BMS345541 | CHEMBL471496 | N-(2-amino...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Uniformed Services University Of The Health Sciences

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 130 total ) | Next | Last >>
Jump to: