Compile Data Set for Download or QSAR
Report error Found 154 of affinity data for UniProtKB/TrEMBL: Q9BVS4
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605906BDBM50605906(CHEMBL5172767)
Affinity DataKd:  6.10nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605906BDBM50605906(CHEMBL5172767)
Affinity DataKd:  7.30nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605907BDBM50605907(CHEMBL5174723)
Affinity DataKd:  7.30nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605908BDBM50605908(CHEMBL5199096)
Affinity DataKd:  8.40nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605909BDBM50605909(CHEMBL5190698)
Affinity DataKd:  18nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619312BDBM50619312(CHEMBL5399070)
Affinity DataKd:  19nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605910BDBM50605910(CHEMBL5184015)
Affinity DataKd:  48nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619313BDBM50619313(CHEMBL5417058)
Affinity DataKd:  48nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605911BDBM50605911(CHEMBL5192566)
Affinity DataKd:  49nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  49nMAssay Description:Binding affinity to RIOK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  49nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  49nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619315BDBM50619315(CHEMBL5417476)
Affinity DataKd:  53nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619316BDBM50619316(CHEMBL5439857)
Affinity DataKd:  56nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605906BDBM50605906(CHEMBL5172767)
Affinity DataIC50: 56nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619314BDBM50619314(CHEMBL5406944)
Affinity DataKd:  62nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605913BDBM50605913(CHEMBL5194039)
Affinity DataKd:  63nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605912BDBM50605912(CHEMBL5190197)
Affinity DataKd:  63nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326053BDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  97nMAssay Description:Binding affinity to RIOK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326053BDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  97nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326053BDBM50326053(PKC-412 | CHEMBL608533 | US20240132489, Compound S...)
Affinity DataKd:  97nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654406BDBM50654406(CHEMBL6145816)
Affinity DataIC50: 98nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605914BDBM50605914(CHEMBL5190993)
Affinity DataKd:  120nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572240BDBM50572240(CHEMBL4857685)
Affinity DataIC50: 130nMAssay Description:Inhibition of RIOK2 in human VCaP cells after 48 hrs by Western blotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605906BDBM50605906(CHEMBL5172767)
Affinity DataIC50: 139nMAssay Description:Inhibition of N-terminal hexahistidine-SUMO-tagged human full length RIOK2 (residues 1 to 321) expressed in Escherichia coli BL21 (DE3) incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31095BDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  140nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634934BDBM50634934(CHEMBL5527885)
Affinity DataKd:  140nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550127BDBM50550127(CHEMBL4781866)
Affinity DataKd:  140nMAssay Description:Binding affinity to RIOK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550127BDBM50550127(CHEMBL4781866)
Affinity DataKd:  150nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550127BDBM50550127(CHEMBL4781866)
Affinity DataKd:  160nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550127BDBM50550127(CHEMBL4781866)
Affinity DataKd:  160nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constant by KdELECT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619317BDBM50619317(CHEMBL5416400)
Affinity DataKd:  165nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572241BDBM50572241(DNDI1417016 | CHEMBL2094383)
Affinity DataKd:  200nMAssay Description:Binding affinity to human RIOK2 assessed as dissociation constant by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605905BDBM50605905(CHEMBL5184068)
Affinity DataKd: <200nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605905BDBM50605905(CHEMBL5184068)
Affinity DataKd: <200nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605915BDBM50605915(CHEMBL5174394)
Affinity DataKd:  200nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd: <200nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31095BDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd: <200nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31095BDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd: <200nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4814BDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd: <200nMAssay Description:Binding affinity to RIOK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572241BDBM50572241(DNDI1417016 | CHEMBL2094383)
Affinity DataKd:  200nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605916BDBM50605916(CHEMBL5187692)
Affinity DataKd:  235nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13534BDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  250nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25118BDBM25118(4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataKd:  260nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605917BDBM50605917(CHEMBL5184335)
Affinity DataKd:  385nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  390nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605918BDBM50605918(CHEMBL5189953)
Affinity DataKd:  455nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550133BDBM50550133(CHEMBL4754518)
Affinity DataKd:  520nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31085BDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  550nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase RIO2(Human)
Jinan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605919BDBM50605919(CHEMBL5177849)
Affinity DataKd:  575nMAssay Description:Binding affinity to wild-type human partial length RIOK2 (M1 to D313 residues) expressed in mammalian expression system assessed as dissociation cons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
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