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Found 14 of affinity data for UniProtKB/TrEMBL: Q9H2S1
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50356161(CHEMBL1909931)
Affinity DataKi:  90nMAssay Description:Displacement of [125I]-apamin from cloned SK2 channel expressed in human HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50356159(CHEMBL1909929)
Affinity DataKi:  194nMAssay Description:Displacement of [125I]-apamin from cloned SK2 channel expressed in human HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50356162(CHEMBL1909932)
Affinity DataKi:  397nMAssay Description:Displacement of [125I]-apamin from cloned SK2 channel expressed in human HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50356158(CHEMBL1909928)
Affinity DataKi:  593nMAssay Description:Displacement of [125I]-apamin from cloned SK2 channel expressed in human HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50356160(CHEMBL1909930)
Affinity DataKi:  878nMAssay Description:Displacement of [125I]-apamin from cloned SK2 channel expressed in human HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Kca2.2 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)
Affinity DataIC50:  59nMAssay Description:Displacement of [125I]apamin from Kca2.2 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50:  123nMAssay Description:Inhibition of Kca2.2 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50275960(5-chloro-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyr...)
Affinity DataIC50:  530nMAssay Description:Inhibition of Kca2.2 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)
Affinity DataIC50:  543nMAssay Description:Displacement of [125I]apamin from Kca2.2 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50275792(CHEMBL452406 | N-benzyl-5-chloropyrazolo[1,5-a]pyr...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Kca2.2 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50377863(AG-525 | CHEMBL257156)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of SK2 expressed in CHO FlipIn cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of SK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
University Of Li£Ge

Curated by ChEMBL
LigandPNGBDBM50275090((1H-Benzoimidazol-2-yl)-(6,7-dichloro-1,2,3,4-tetr...)
Affinity DataKd:  47nMAssay Description:Inhibition of human SK2 channel by inside-out patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed