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Report error Found 269 of affinity data for UniProtKB/TrEMBL: Q9Y6E0
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human MST3 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human MST3 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human MST3 using myelin basic protein as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of STK24More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human MST3 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50161957(CHEMBL180022 | N-(4-(3-chloro-4-(pyridin-2-ylmetho...)
Affinity DataKd:  6.5nMAssay Description:Binding constant for MST3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50161957(CHEMBL180022 | N-(4-(3-chloro-4-(pyridin-2-ylmetho...)
Affinity DataIC50: 7nMAssay Description:Inhibition of MST3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50273571(Hesperadin | TCMDC-135395 | N-(2-oxo-3-(phenyl(4-(...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MST3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641160(CHEMBL5571948)
Affinity DataEC50:  10nMAssay Description:Inhibition of MST3 (unknown origin) expressed in lysed HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 11.8nMAssay Description:Inhibition of human MST3 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50583996(CHEMBL4554938 | US12318398, Compound XMU-MP-1)
Affinity DataKd:  18nMAssay Description:Binding affinity to MST3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641157(CHEMBL5571159)
Affinity DataEC50:  20nMAssay Description:Inhibition of MST3 (unknown origin) expressed in lysed HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641157(CHEMBL5571159)
Affinity DataEC50:  20nMAssay Description:Inhibition of MST3 (unknown origin) expressed in intact HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641158(CHEMBL5569777)
Affinity DataEC50:  23nMAssay Description:Inhibition of MST3 (unknown origin) expressed in lysed HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641153(CHEMBL5565155)
Affinity DataEC50:  27nMAssay Description:Inhibition of MST3 (unknown origin) expressed in lysed HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641156(CHEMBL5590480)
Affinity DataEC50:  33nMAssay Description:Inhibition of MST3 (unknown origin) expressed in lysed HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641159(CHEMBL5594538)
Affinity DataEC50:  34nMAssay Description:Inhibition of MST3 (unknown origin) expressed in lysed HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641147(CHEMBL5567421)
Affinity DataEC50:  42nMAssay Description:Inhibition of MST3 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641147(CHEMBL5567421)
Affinity DataEC50:  42nMAssay Description:Inhibition of MST3 (unknown origin) expressed in lysed HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50148921(CHEMBL3770443)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant MST3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50583996(CHEMBL4554938 | US12318398, Compound XMU-MP-1)
Affinity DataIC50: 45nMAssay Description:Inhibition of MST3 (unknown origin) in presence of ATP by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641150(CHEMBL5575508)
Affinity DataEC50:  48nMAssay Description:Inhibition of MST3 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641153(CHEMBL5565155)
Affinity DataEC50:  55nMAssay Description:Inhibition of MST3 (unknown origin) expressed in intact HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641154(CHEMBL5566570)
Affinity DataEC50:  56nMAssay Description:Inhibition of MST3 (unknown origin) expressed in lysed HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641152(CHEMBL5572995)
Affinity DataEC50:  57nMAssay Description:Inhibition of MST3 (unknown origin) expressed in lysed HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641151(CHEMBL5573797)
Affinity DataEC50:  57nMAssay Description:Inhibition of MST3 (unknown origin) expressed in intact HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641149(CHEMBL5555859)
Affinity DataEC50:  60nMAssay Description:Inhibition of MST3 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  63nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  63nMAssay Description:Binding constant for MST3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  63nMAssay Description:Binding constant for MST3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  63nMAssay Description:Binding affinity to MST3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641444(CHEMBL5562742)
Affinity DataEC50:  80nMAssay Description:Binding affinity to C-terminal full length human MST3 expressed in permeabilized HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641151(CHEMBL5573797)
Affinity DataEC50:  81nMAssay Description:Inhibition of MST3 (unknown origin) expressed in lysed HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641148(CHEMBL5567287)
Affinity DataEC50:  92nMAssay Description:Inhibition of MST3 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  100nMAssay Description:Binding constant for MST3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  100nMAssay Description:Binding constant for MST3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  100nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641444(CHEMBL5562742)
Affinity DataEC50:  110nMAssay Description:Binding affinity to C-terminal full length human MST3 expressed in intact HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | Vargatef | US10981896, Co...)
Affinity DataKd:  110nMAssay Description:Binding constant for MST3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM50641162(CHEMBL5573230)
Affinity DataEC50:  115nMAssay Description:Inhibition of MST3 (unknown origin) expressed in lysed HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  120nMAssay Description:Binding constant for MST3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  120nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  120nMAssay Description:Binding affinity to recombinant MST3 (unknown origin) assessed as dissociation constant by DSF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM451730(4-(6-amino-5-(1-oxo-1,2,3,4- tetrahydroisoquinolin...)
Affinity DataIC50: 120nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM451766(4-(6-amino-5-(1-oxo-1,2,3,4- tetrahydroisoquinolin...)
Affinity DataIC50: 120nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataEC50:  120nMAssay Description:Inhibition of MST3 (unknown origin) expressed in intact HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  120nMAssay Description:Binding affinity to MST3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  120nMAssay Description:Binding constant for MST3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM451741(N-(4-(6-amino-5-(1-oxo- 1,2,3,4-tetrahydroisoquino...)
Affinity DataIC50: 120nMAssay Description:Biochemical IC50s were measured at Invitrogen using Z-lyte technology. Briefly, for STK4, the 2×STK4 (MST1)/Ser/Thr 07 mixture was prepared in 50 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase 24(Human)
Gachon University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataEC50:  120nMAssay Description:Inhibition of MST3 (unknown origin) expressed in HEK293T cells using NanoGlo as substrate incubated for 20 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
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