PMID

Data

Article Title

Organization

Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain.

University of Siena

a-Ketoheterocycle inhibitors of fatty acid amide hydrolase: exploration of conformational constraints in the acyl side chain.

The Scripps Research Institute

Design, synthesis, and characterization ofa-ketoheterocycles that additionally target the cytosolic port Cys269 of fatty acid amide hydrolase.

The Scripps Research Institute

(4-Phenoxyphenyl)tetrazolecarboxamides and related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL).

University of M£Nster

Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties.

Universit£

Synthesis of 61-bis(1-adamantylcarbamoyl)-1,2-methano[60]fullerene and its antagonistic effect on haloperidol-induced catalepsy in mice.

Kyushu University

Discovery of potent inhibitors of human and mouse fatty acid amide hydrolases.

Universit£

The discovery and development of inhibitors of fatty acid amide hydrolase (FAAH).

The Scripps Research Institute

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects.

The Scripps Research Institute

Activation of the endocannabinoid system by organophosphorus nerve agents.

University of California

A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.

Università

Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases.

The Scripps Research Institute

Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels.

University of California

Discovery of an exceptionally potent and selective class of fatty acid amide hydrolase inhibitors enlisting proteome-wide selectivity screening: concurrent optimization of enzyme inhibitor potency and selectivity.

The Scripps Research Institute

Arachidonylsulfonyl derivatives as cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors.

University of California

Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems.

University of Siena

N-Acyl pyrazoles: Effective and tunable inhibitors of serine hydrolases.

The Scripps Research Institute

Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase.

University of California Davis

Therapeutic Potential of Fatty Acid Amide Hydrolase, Monoacylglycerol Lipase, and N-Acylethanolamine Acid Amidase Inhibitors.

Universit£

Novel propanamides as fatty acid amide hydrolase inhibitors.

University of Cagliari

The first selective agonist for the neuropeptide YY5 receptor increases food intake in rats.

Federal Institute of Technology of Zurich

Cloning and functional expression of a cDNA encoding a human type 2 neuropeptide Y receptor.

Bristol-Myers Squibb

Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone (R547), a potent and selective cyclin-dependent kinase inhibitor with significant in vivo antitumor activity.

Hoffmann-La Roche