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Found 5 Enz. Inhib. hit(s) with all data for entry = 50032134
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US11753371, Compound JZL-184 | US91...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant FAAH expressed in Cos7 cells after 30 mins by using anandamide as a substrate by LC-MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US11753371, Compound JZL-184 | US91...)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant MAGL expressed in Cos7 cells after 30 mins by using 2-AG as a substrate by LC-MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US11753371, Compound JZL-184 | US91...)
Affinity DataIC50:  8nMAssay Description:Inhibition of MAGL in C57B1/6J mouse brain membrane after 30 mins by using 2-AG as a substrate by LC-MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US11753371, Compound JZL-184 | US91...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of FAAH in C57B1/6J mouse brain membrane after 20 mins by using oleamide as a substrate by LC-MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50128581(Biphenyl-3-yl-carbamic acid cyclohexyl ester | CHE...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of MAGL in Wistar rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed