BDBM86053 B-HT 920::CAS_101626-70-4::CHEMBL279085::NSC_104870::Talipexole::cid_5374
SMILES Nc1nc2CCN(CC=C)CCc2s1
InChI Key InChIKey=DHSSDEDRBUKTQY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 33 hits for monomerid = 86053
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 5.80nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetD(3) dopamine receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetD(4) dopamine receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetD(2) dopamine receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetD(2) dopamine receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Wyeth-Ayerst Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.70E+3nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the antagonist [3H]spiperone + GTP to label the low affinity stat...More data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
TargetMu-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: 9.25E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Assay Provider: Laura Bohn External Assay ID: OPRM1_AC...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:Binding affinity against alpha-1 adrenergic receptor is the ability to inhibit the specific [3H]-prazosin binding (0.2 nM) to rat isolated brain memb...More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain memb...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Mus musculus (Mouse))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataEC50: 7.61E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair