BDBM35667 AVP::CHEMBL373742::US10131692, 44 (AVP)::[3H]Arginine vasopressin::[3H]Argipressin tannate::[3H]vasopressin
SMILES [#7]-[#6@H]-1-[#6]-[#16]-[#16]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccccc2)-[#7]-[#6](=O)-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#7]-[#6]-1=O)-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](-[#7])=O
InChI Key InChIKey=KBZOIRJILGZLEJ-LGYYRGKSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 29 hits for monomerid = 35667
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical
Curated by PDSP Ki Database
Yamanouchi Pharmaceutical
Curated by PDSP Ki Database
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1b receptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1a receptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Second Tokushima Institute Of New Drug Research
Curated by PDSP Ki Database
Second Tokushima Institute Of New Drug Research
Curated by PDSP Ki Database
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical
Curated by PDSP Ki Database
Yamanouchi Pharmaceutical
Curated by PDSP Ki Database
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]AVP from rat OT receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Second Tokushima Institute Of New Drug Research
Curated by PDSP Ki Database
Second Tokushima Institute Of New Drug Research
Curated by PDSP Ki Database
Affinity DataKi: 1.36nMAssay Description:Displacement of [3H]-AVP from human vasopressin V2 receptor expressed in CHO cells after 30 mins by saturation binding assayMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Second Tokushima Institute Of New Drug Research
Curated by PDSP Ki Database
Second Tokushima Institute Of New Drug Research
Curated by PDSP Ki Database
Affinity DataKi: 1.48nMAssay Description:Displacement of [3H]-AVP from human vasopressin V2 receptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.65nMAssay Description:Displacement of [3H]-AVP from human oxytocin receptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]AVP from human oxytocin receptor expressed CHO cells after 60 minsMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical
Curated by PDSP Ki Database
Yamanouchi Pharmaceutical
Curated by PDSP Ki Database
TargetVasopressin V2 receptor(Rattus norvegicus (Rat))
Yamanouchi Pharmaceutical
Curated by PDSP Ki Database
Yamanouchi Pharmaceutical
Curated by PDSP Ki Database
Affinity DataKd: 1.5nMAssay Description:Compound was evaluated for its dissociation constant (Kd) to rat kidney Vasopressin V2 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 8.30nMAssay Description:Agonist activity at human oxytocin receptor expressed CHO cells assessed as induction of phospholipase C activity after 15 mins by inositol phosphate...More data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Agonist activity at human OT receptor expressed in CHO-K1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Agonist activity at human OT receptor expressed in CHO-K1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Tested for the inhibition to V2 subtype receptor using [3H]- (VS2) as radioligand at 3 nM and arginine-vasopressin at 2 microM in LLCPKI cellsMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Second Tokushima Institute Of New Drug Research
Curated by PDSP Ki Database
Second Tokushima Institute Of New Drug Research
Curated by PDSP Ki Database
Affinity DataIC50: 242nMAssay Description:Binding affinity to vasopression V2 receptor (unknown origin) on isolated cell membrane by vasopression-self competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.650nMAssay Description:Compound was evaluated for its dissociation constant (Kd) to rat liver Vasopressin V1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Tested for the TYR(Me)2 arginine-vasopressin as radioligand at 0.3 nM in A7r5 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 0.646nMAssay Description:Negative log of Kd for Vasopressin V1 receptorMore data for this Ligand-Target Pair
TargetVasopressin V2 receptor(Homo sapiens (Human))
Second Tokushima Institute Of New Drug Research
Curated by PDSP Ki Database
Second Tokushima Institute Of New Drug Research
Curated by PDSP Ki Database
Affinity DataEC50: 40nMAssay Description:Agonist activity of compounds on the human V2 receptor (h V2R) was determined in a transcriptional reporter gene assay by transiently transfecting an...More data for this Ligand-Target Pair
Affinity DataKd: 1.5nMAssay Description:Inhibition of radioligand [3H]AVP binding to V2 receptor in bovine kidney inner medulla membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 5.40E+3nMAssay Description:To determine selectivity, compounds were tested in luciferase-based transcriptional reporter gene assays expressing the human V1b receptor (hV1bR). A...More data for this Ligand-Target Pair
Affinity DataKd: 0.640nMAssay Description:Binding potency against V1 receptor in rat liver cellsMore data for this Ligand-Target Pair