BDBM50000407 2-carboxypyridine::CHEMBL72628::alpha-picolinic acid::alpha-pyridinecarboxylic acid::o-pyridinecarboxylic acid::picolinic acid::pyridine-2-carboxylic acid
SMILES OC(=O)c1ccccn1
InChI Key InChIKey=SIOXPEMLGUPBBT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50000407
Affinity DataKi: 5.70E+3nMAssay Description:Inhibition of Aeromonas hydrophila beta lactamase CphA by competitive inhibition assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+4nMAssay Description:Inhibition of Aeromonas hydrophila beta lactamase CphA at pH 7.0More data for this Ligand-Target Pair
Affinity DataKi: 7.60E+4nMAssay Description:Inhibition of Aeromonas hydrophila beta lactamase CphA at pH 8.0More data for this Ligand-Target Pair
Affinity DataKi: 4.40E+5nMAssay Description:Inhibition of Aeromonas hydrophila beta lactamase CphA at pH 9.0More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+6nMAssay Description:Inhibition of Aeromonas hydrophila beta lactamase CphA at pH 10.0More data for this Ligand-Target Pair
TargetProton-coupled amino acid transporter 1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 1.80E+7nMAssay Description:Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation countingChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+6nMAssay Description:Inhibition of native signal containing Klebsiella pneumoniae OXA-48 using nitrocefin substrate pre-incubated for 5 mins before substrate additionMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to native signal deficient and TEV cleavage site containing His-tagged Klebsiella pneumoniae OXA-48 expressed in Escherichia coli as...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Ici Pharmaceuticals Group
Curated by ChEMBL
Ici Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:In vitro inhibibition of dihydrodipicolinic acid synthase.More data for this Ligand-Target Pair