BDBM50002334 1-(4-Fluoro-phenyl)-4-(4-pyrimidin-2-yl-piperazin-1-yl)-butan-1-one::4-[4-(2-Pyrimidine)piperazin-1-yl]-1-(4-fluorophenyl)-butan-1-one::CHEMBL140872

SMILES: Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ncccn1

InChI Key: InChIKey=WEVJMQOBCRCIPF-UHFFFAOYSA-N

Data: 15 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50002334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rat)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	679	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Rat)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Rat)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		6.53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		30.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		30.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		244	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		244	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		912	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		912	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Rat)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		4.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50002334 (CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...) Show SMILES Show InChI	GoogleScholar	UniChem		4.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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