BDBM50328457 CHEMBL1258494::N-[4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl]-2,5-dimethylbenzamide

SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc(C)ccc2C)CC1

InChI Key InChIKey=AAYMNPGQEZYHNE-UHFFFAOYSA-N

Data  5 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50328457   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328457(CHEMBL1258494 | N-[4-[4-(2-Methoxyphenyl)piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc(C)ccc2C)CC1
Show InChI InChI=1S/C24H33N3O2/c1-19-10-11-20(2)21(18-19)24(28)25-12-6-7-13-26-14-16-27(17-15-26)22-8-4-5-9-23(22)29-3/h4-5,8-11,18H,6-7,12-17H2,1-3H3,(H,25,28)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328457(CHEMBL1258494 | N-[4-[4-(2-Methoxyphenyl)piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc(C)ccc2C)CC1
Show InChI InChI=1S/C24H33N3O2/c1-19-10-11-20(2)21(18-19)24(28)25-12-6-7-13-26-14-16-27(17-15-26)22-8-4-5-9-23(22)29-3/h4-5,8-11,18H,6-7,12-17H2,1-3H3,(H,25,28)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328457(CHEMBL1258494 | N-[4-[4-(2-Methoxyphenyl)piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc(C)ccc2C)CC1
Show InChI InChI=1S/C24H33N3O2/c1-19-10-11-20(2)21(18-19)24(28)25-12-6-7-13-26-14-16-27(17-15-26)22-8-4-5-9-23(22)29-3/h4-5,8-11,18H,6-7,12-17H2,1-3H3,(H,25,28)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(PIG)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328457(CHEMBL1258494 | N-[4-[4-(2-Methoxyphenyl)piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc(C)ccc2C)CC1
Show InChI InChI=1S/C24H33N3O2/c1-19-10-11-20(2)21(18-19)24(28)25-12-6-7-13-26-14-16-27(17-15-26)22-8-4-5-9-23(22)29-3/h4-5,8-11,18H,6-7,12-17H2,1-3H3,(H,25,28)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]Ketanserin from 5-HT2 receptor in pig cortex membranesMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Sus scrofa)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50328457(CHEMBL1258494 | N-[4-[4-(2-Methoxyphenyl)piperazin...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc(C)ccc2C)CC1
Show InChI InChI=1S/C24H33N3O2/c1-19-10-11-20(2)21(18-19)24(28)25-12-6-7-13-26-14-16-27(17-15-26)22-8-4-5-9-23(22)29-3/h4-5,8-11,18H,6-7,12-17H2,1-3H3,(H,25,28)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in pig striatal membranesMore data for this Ligand-Target Pair