BDBM50420259 CEFTAZIDIME

SMILES CC(C)(O\N=C(/C(=O)N[C@H]1[C@H]2SCC(C[n+]3ccccc3)=C(N2C1=O)C([O-])=O)c1csc(N)n1)C(O)=O

InChI Key InChIKey=ORFOPKXBNMVMKC-DWVKKRMSSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50420259   

TargetSolute carrier family 15 member 2(Rattus norvegicus)
Biozentrum of The Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50420259(CEFTAZIDIME)
Affinity DataKi: >1.00E+7nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in SKPT cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
Biozentrum of The Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50420259(CEFTAZIDIME)
Affinity DataKi: >1.00E+7nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptidase(Staphylococcus aureus)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50420259(CEFTAZIDIME)
Affinity DataIC50: >9.14E+4nMAssay Description:Inhibition of bocillin FL binding to methicillin-resistant Staphylococcus aureus OC 3726 penicillin-binding protein 2aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 1B(Pseudomonas aeruginosa)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50420259(CEFTAZIDIME)
Affinity DataIC50:  9.14E+3nMAssay Description:Inhibition of bocillin FL binding to Pseudomonas aeruginosa PAO1 penicillin-binding protein 1bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Pseudomonas aeruginosa)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50420259(CEFTAZIDIME)
Affinity DataIC50: >5.85E+4nMAssay Description:Inhibition of bocillin FL binding to Pseudomonas aeruginosa PAO1 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase FtsI(Pseudomonas aeruginosa)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50420259(CEFTAZIDIME)
Affinity DataIC50:  182nMAssay Description:Inhibition of bocillin FL binding to Pseudomonas aeruginosa PAO1 penicillin-binding protein 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50420259(CEFTAZIDIME)
Affinity DataIC50:  7.31E+3nMAssay Description:Inhibition of bocillin FL binding to Escherichia coli MC4100 penicillin-binding protein 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed