BDBM82258 CAS_114798-26-4::Losartan::NSC_3961

SMILES: CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=PSIFNNKUMBGKDQ-UHFFFAOYSA-N

Data: 20 KI  54 IC50  8 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 82 hits for monomerid = 82258   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-2 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.62	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Rabbit)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16.2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Type-1 angiotensin II receptor (Bovine)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor (Rat)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Rabbit)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A (Rat)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Angiotensin-converting enzyme (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1/Type-2 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Rabbit)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Rabbit)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	61.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Rabbit)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16.2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Rabbit)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1/Type-2 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor (Rat)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet glycoprotein VI (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet glycoprotein VI (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet glycoprotein VI (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A (Rat)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier organic anion transporter family member 1B3 (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier organic anion transporter family member 1B1 (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	288	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug and toxin extrusion protein 1 (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Rabbit)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.58	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Rabbit)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.72	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1/Type-2 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (Rat)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (Rat)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1/Type-2 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor (Rat)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (Rat)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor (Rat)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (Rat)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (Rat)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (Rat)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A (Mouse)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Platelet glycoprotein VI (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Human)	BDBM82258 (NSC_3961 | CAS_114798-26-4 | Losartan) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
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